口服补钙对铁、锌代谢影响的临床研究  

Clinical Investigation in Effect of Oral Calcium Intake on Iron and Zinc Metabolism

作　　者：姜梅[1] 郗春艳[1] 赵亚茹 

机构地区：[1]中国医科大学第二临床学院基础儿科,沈阳110003

出　　处：《中华儿童保健杂志》1997年第4期227-229,共3页

摘　　要：观察口服补钙对铁、锌代谢的影响.方法给以相同饮的幼儿园儿童口服补钙每日130mg,连续2个月.观察其血常规、血清铁、锌的变化.结果实验组与对照组相比,补钙儿童血清铁降低;红细胞休积分布宽度增加;血红蛋白、红细胞平均血红蛋白及血清锌无明显变化.结论口服补钙可能影响饮食铁的吸收,致循环铁减少,并影响红细胞生成缺铁;而常规剂量补钙2个月对锌代谢无明显影响.To investigate the effect of oral calcium intake on iron and zinc metabolism. Methods The dose of daily 130mg calcium was administered to 32 children, and placebo was administered to the control groups who had 27 children with the same diet for 2 months. Before and after the administration, the hemoglobin (HGB), mean cell hemoglobin(MCH) and red cell distrabution (RDW), serum zinc and serum iron was massured. Results 2 months later, the serum iron and RDW of calcium supplemental groups was lower and higher significiently than that of control groups respectively; The HGB, MCH, and serum zine didn't have significient change. Conclusion Daily oral calcium intake may has effect on iron absorption. Circulation iron and erythro-cytegrowing iron were reduced, but this dose of calcium intake has no effect on zinc metabolism.

关 键 词：口服补钙 铁代谢 锌代谢 儿童 

分 类 号：R151.2[医药卫生—营养与食品卫生学] R153.2[医药卫生—公共卫生与预防医学]