葡糖基转移酶抗体的防龋研究  

Anticaries of Glucosyltransferase antibodies

作　　者：赵建[1] 宋长征[1] 韩金祥[1] 黄海南[1] 王美岭[1] 

机构地区：[1]山东省医学科学院生物技术中心,济南250052

出　　处：《中华儿童保健杂志》1997年第4期270-271,共2页

基　　金：生物防龋制剂的研制;鲁科技(1995)第137号课题;序号33(3)

摘　　要：为了从病因学的角度对龋齿进行有效防治.方法 通过测定使用从免疫乳中提取的葡糖基转移酶抗体后,对唾液中游离型该酶的活性影响,及儿童近期新龋发生率的观察和比较. 结果 该抗体可显著降低口腔唾液中游离型萄糖基转移酶的活性,并取得明显近期防龋作用.结论 该方法是一种安全可靠的防龋新途径.In order to prevention of dental caries from its etiology. Methods Through oral administration of glucosyltransferase antibodies from immune milk, the effect on levels of free glucdsyltransterase in saliva and on occurrence of caries was studied and compared. Result The activities of free glucosyltransterase was significantly reduced by the antiboodies . A recent anticarious effect was also observed. Conclusion glucosyltransferase antitody was a safe, reliable way of anticaries.

关 键 词：葡糖基转移酶 抗体 防龋 儿童 

分 类 号：R788.101[医药卫生—口腔医学]