眼局部肾素血管紧张素系统与青光眼  

Current progress of ocular renin-Angiotensin system and glaucoma

作　　者：章艳[1,2] 熊新春[1] 

机构地区：[1]华中科技大学协和医院眼科,武汉430000 [2]宜昌市第一人民医院眼科,443000

出　　处：《眼科研究》2008年第12期957-960,共4页Chinese Ophthalmic Research

基　　金：湖北省自然科学基金资助(2006ABA135)

摘　　要：青光眼的发生和发展是多因素造成的,治疗和预防也是多方面的。随着研究的深入,眼局部组织的肾素血管紧张素系统(RAS)在这一疾病中的作用日益受到重视。就RAS在青光眼的诊断、治疗及病理生理中的作用进行综述。Glaucoma is characterized by elevated intraocular pressure associated with optic disk cupping and visual field loss. So glaucoma become one of leading causes of blindness. There are many factors can lead to glaucoma, and high intraocular pressure （IOP） has been shown to be a key risk factor for the rehibitation of visual acuity in glaucoma. The treatments and the precautions of glaucoma are comprehensive. Recently years, the roles of the local renin-Angiotensin system （RAS） are studied more and more,and the influence of the RAS on glaucoma also was payed close attention. The local renin-Angiotensin system （RAS） is widely existed in majority of eye tissues and plays important role in regulating aqueous humour dynamics and therefore IOP. Effects of RAS on the diagnosis,treatment,pathology and progress of glaucoma were discussed in this article.

关 键 词：肾素血管紧张素系统 青光眼 眼压 

分 类 号：R775[医药卫生—眼科]