Manipulation on human red blood cells with femtosecond optical tweezers  

作　　者：周明 杨海峰 狄建科 赵恩兰 

机构地区：[1]Photonics Fabrication Science Center Jiangsu University

出　　处：《Chinese Optics Letters》2008年第12期919-921,共3页中国光学快报（英文版）

基　　金：supported by the National"863"Program of China(No.2006AA04Z307);the Foundation for the Author of National Excellent Doctoral Dissertation of China(No.2006039);the National Natural Science Foundation of China(No.50775140);the Natural Science Foundation of Jiangsu Province(No.BK2006507);the Jiangsu Province Research Innovation Program of College Graduate(No.CX07B_086z).

摘　　要：Different types of femtosecond optical tweezers have become a powerful tool in the modern biological field. However, how to control the irregular targets, including biological cells, using femtosecond optical tweezers remains to be explored. In this study, human red blood cells （hRBCs） are manipulated with femtosecond optical tweezers, and their states under different laser powers are investigated. The results indicate that optical potential traps only can capture the edge of hRBCs under the laser power from 1.4 to 2.8 mW, while it can make hRBCs turn over with the laser power more than 2.8 mW. It is suggested that femtosecond optical tweezers could not only manipulate biological cells, but also subtly control its states by adjusting the laser power.Different types of femtosecond optical tweezers have become a powerful tool in the modern biological field. However, how to control the irregular targets, including biological cells, using femtosecond optical tweezers remains to be explored. In this study, human red blood cells （hRBCs） are manipulated with femtosecond optical tweezers, and their states under different laser powers are investigated. The results indicate that optical potential traps only can capture the edge of hRBCs under the laser power from 1.4 to 2.8 mW, while it can make hRBCs turn over with the laser power more than 2.8 mW. It is suggested that femtosecond optical tweezers could not only manipulate biological cells, but also subtly control its states by adjusting the laser power.

关 键 词：BLOOD Hemoglobin oxygen saturation Laser optics LASERS Optical instruments Pulsed laser deposition 

分 类 号：Q2-3[生物学—细胞生物学]