BLOOD

作品数：1431被引量：2632H指数：18
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Chitosan alleviates symptoms of Parkinson's disease by reducing acetate levels, which decreases inflammation and promotes repair of the intestinal barrier and blood–brain barrier
《Neural Regeneration Research》2026年第1期377-391,共15页Yinying Wang Rongsha Chen Guolin Shi Xinwei Huang Ke Li Ruohua Wang Xia Cao Zhongshan Yang Ninghui Zhao Jinyuan Yan 
supported by the National Natural Science Foundation of China,Nos. 32260196 (to JY), 81860646 (to ZY) and 31860274 (to JY);a grant from Yunnan Department of Science and Technology,Nos. 202101AT070251 (to JY), 202201AS070084 (to ZY), 202301AY070001-239 (to JY), 202101AZ070001-012, and 2019FI016 (to ZY)。
Studies have shown that chitosan protects against neurodegenerative diseases. However, the precise mechanism remains poorly understood. In this study, we administered chitosan intragastrically to an MPTP-induced mouse...
关键词：ACETATE adenosine 5′-monophosphate-activated protein kinase blood–brain barrier CHITOSAN dopamine neurons INFLAMMATION intestinal barrier Parkinson's disease peroxisome proliferator-activated receptor delta short-chain fatty acids 
Blood diagnostic and prognostic biomarkers in amyotrophic lateral sclerosis被引量：1
《Neural Regeneration Research》2025年第9期2556-2570,共15页Yongting Lv Hongfu Li 
Amyotrophic lateral sclerosis is a devastating neurodegenerative disease for which the current treatment approaches remain severely limited.The principal pathological alterations of the disease include the selective d...
关键词：amyotrophic lateral sclerosis BIOMARKER blood biomarkers diagnosis glial fibrillary acidic protein neurofilament light chain PROGNOSIS TAR DNA-binding protein 43 
Beyond wrecking a wall:revisiting the concept of blood–brain barrier breakdown in ischemic stroke被引量：1
《Neural Regeneration Research》2025年第7期1944-1956,共13页Julia Castillo-González Elena González-Rey 
supported by the grants from the Spanish Ministry of Economy and Competitiveness(SAF2017-85602-R);the Spanish Ministry of Science and Innovation(PID2020-119638RB-I00 to EGR);FPU-program(FPU17/02616 to JCG)。
The blood–brain barrier constitutes a dynamic and interactive boundary separating the central nervous system and the peripheral circulation.It tightly modulates the ion transport and nutrient influx,while restricting...
关键词：blood–brain barrier disruption drug delivery ischemic stroke NEUROINFLAMMATION tight-junctions 
Landscape of chimeric RNAs in COVID-19 patient blood
《Genes & Diseases》2025年第3期599-610,共12页Samuel Haddox Ping Wu Sandeep Singh Fujun Qin Jack Engel Andrea Kian Syed Ahmad Hui Li Peng Wu 
supported by the National Institutes of Health(USA)(No.R01GM132138 to H.L.).
Despite the availability of efficacious vaccines, COVID-19 persists and our knowledge of how SARS-CoV-2 infection affects host transcriptomics remains incomplete. Transcriptome analysis, which has progressed our under...
关键词：BLOOD Chimeric RNA COVID-19 PTBP1 SARS-CoV-2 
MicroRNAs as potential diagnostic biomarkers for bipolar disorder
《Neural Regeneration Research》2025年第6期1681-1695,共15页Bridget Martinez Philip V.Peplow 
Abnormal expression of microRNAs is connected to brain development and disease and could provide novel biomarkers for the diagnosis and prognosis of bipolar disorder. We performed a PubMed search for microRNA biomarke...
关键词：BIOMARKER bipolar disorder blood leukocytes blood plasma blood plasma extracellular vesicles/exosomes blood serum brain tissue brain tissue extracellular vesicles/exosomes lymphoblastoid cell lines MICRORNA neural progenitor cells whole blood 
Antihemorrhagic Effect of the Extract from Blumea megacephala (Randeria) Chang et Tseng on the Uterine Bleeding Model in Early Pregnancy Rats
《Medicinal Plant》2025年第2期40-43,48,共5页Xixue NA Shenggao YIN Wentao ZHANG Yuanfeng TAN Wei WEI Xiaoqing NING 
Supported by the University-level Project of Guangxi University of Chinese Medicine(2021ZD005).
[Objectives]To investigate the effect of extract A from Blumea megacephala(Randeria)Chang et Tseng on the hemostasis of postpartum uterine hemorrhage in early pregnancy rats.[Methods]12 mg/kg of mifepristone and 120μ...
关键词：Blumea megacephala(Randeria)Chang et Tseng Uterine hemorrhage model of early pregnancy rats HEMOSTASIS Blood vessel BLOOD 
Fucoidan protects against LPS-induced mastitis and enhances the integrity of blood-milk barrier by activating AMPK/Nrf2 and autophagy
《Food Science and Human Wellness》2025年第2期594-604,共11页Xiaoben Liang Yuhong Chen Zhijie Zheng Yonghui Zheng Haichong Wu 
funded by the National Natural Science Foundation of China(32102733);the Zhejiang Provincial Natural Science Foundation of China(LQ22C180004);the Longyan University&Fujian Provincial Key Laboratory for Prevention and Control of Animal Infectious Diseases and Biotechnology(ZDSYS2022002)。
Mastitis often occurs during women's lactation period,causing great psychological and physical pain to women.Fucoidan,a sulfated polysaccharide obtained from brown algae,has much broader biological properties.However,...
关键词：FUCOIDAN MASTITIS Blood-milk barrier AUTOPHAGY AMPK/Nrf2 
Blood-based machine learning classifiers for early diagnosis of gastric cancer via multiple miRNAs
《World Journal of Gastrointestinal Oncology》2025年第4期416-426,共11页Fu-Chao Ma Guan-Lan Zhang Bang-Teng Chi Yu-Lu Tang Wei Peng Ai-Qun Liu Gang Chen Jin-Biao Gao Dan-Ming Wei Lian-Ying Ge 
Supported by the Guangxi Zhuang Autonomous Region Health Commission Scientific Research Project,No.Z-A20220465;Guangxi Key R and D Plan,No.AB20297021;Guangxi Medical and Health Appropriate Technology Development and Promotion Application Project,No.S2022107;China Undergraduate Innovation and Entrepreneurship Training Program,No.S202310598074;Future Academic Star of Guangxi Medical University,No.WLXSZX23109.
BACKGROUND Early screening methods for gastric cancer(GC)are lacking;therefore,the disease often progresses to an advanced stage when patients first start to exhibit typical symptoms.Endoscopy and pathological biopsy ...
关键词：Gastric cancer miRNA Biological marker Machine learning SERUM 
Effects of Vibrio anguillarum Infection on Blood Homeostasis,Gut Microbiota and Transcriptome Profiling in Chinese Seabass(Lateolabrax maculatus)
《Journal of Ocean University of China》2025年第2期448-462,共15页MING Jiagen SU Dongyan HAN Xiufeng WU Xiangyang LI Bo TAN Jiabo SONG Xiaojun 
received funding from the Natural Science Foundation of Shandong Province(No.ZR2023MC141);the Innovation and Entrepreneurship Training Program for College Students(No.202210435003);financial support was also provided by the‘First Class Fishery Discipline’Program and the Special Talent Program‘One Thing One Decision(Yishi Yiyi)’in Shandong Province,China。
The Chinese seabass(Lateolabrax maculatus)is one of the most popular and valuable aquaculture species in China.Recently,the disease caused by Vibrio anguillarum has brought huge economic losses in the L.maculatus indu...
关键词：Lateolabrax maculatus Vibrio anguillarum blood homeostasis immune response gut microbiota TRANSCRIPTOME 
Effect of Acupuncture Combined with Nerve Block on Cerebral Functional Area Blood Perfusion in Treatment of Alzheimer's Disease:A Case Report
《Chinese Journal of Integrative Medicine》2025年第4期357-359,共3页GAO Xiu-mei LIU Huan 
Supported by Scientific and Technological Innovation Project of China Academy of Chinese Medical Sciences (No. CI2021B00)。
Alzheimer's disease(AD)is a prevalent neurodegenerative disorder among the elderly population,and timely intervention has been shown to effectively slow down the progression of dementia stage.(1)Although drugs such as...
关键词：enhance cognitive abilities cerebral functional area blood perfusion alzheimers disease ad improving cerebral blood ameliorate memory loss neurodegenerative disorder nerve block timely intervention 
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