FUCOIDAN

作品数：58被引量：119H指数：6
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Fucoidan protects against LPS-induced mastitis and enhances the integrity of blood-milk barrier by activating AMPK/Nrf2 and autophagy
《Food Science and Human Wellness》2025年第2期594-604,共11页Xiaoben Liang Yuhong Chen Zhijie Zheng Yonghui Zheng Haichong Wu 
funded by the National Natural Science Foundation of China(32102733);the Zhejiang Provincial Natural Science Foundation of China(LQ22C180004);the Longyan University&Fujian Provincial Key Laboratory for Prevention and Control of Animal Infectious Diseases and Biotechnology(ZDSYS2022002)。
Mastitis often occurs during women's lactation period,causing great psychological and physical pain to women.Fucoidan,a sulfated polysaccharide obtained from brown algae,has much broader biological properties.However,...
关键词：FUCOIDAN MASTITIS Blood-milk barrier AUTOPHAGY AMPK/Nrf2 
A novel enzyme-assisted one-pot method for the extraction of fucoidan and alginate oligosaccharides from Lessonia trabeculata and their bioactivities
《Journal of Oceanology and Limnology》2024年第6期1998-2012,共15页Changhui YAN Mingxuan PAN Lihua GENG Quanbin ZHANG Yadong HU Jing WANG Sujuan YE 
Supported by the Jiangsu Coast Development Group Co.,Ltd.;the Marine Biological High Value Development and Utilization Project(No.2023YHTZZZ04);the Natural Science Foundation of Shandong Province(No.ZR2022MD007);the Science and Technology Project of Fujian Province(Nos.2022T3024,2023T3057)。
Alginate oligosaccharides(AOS)and fucoidan are two important bioactive carbohydrate which that can be prepared from brown seaweeds.We investigated a novel enzyme-assisted one-pot method on AOS and fucoidan extraction ...
关键词：Lessonia trabeculata alkaline digestion-enzymatic hydrolysis alginate oligosaccharides FUCOIDAN antioxidant activity 
Advances in Biomedical Applications of Hydrogels from Seaweed-Derived Sulfated Polysaccharides:Carrageenan,Fucoidan,and Ulvan
《Journal of Ocean University of China》2024年第5期1329-1346,共18页CUI Zhiyong JIANG Fei LI Luxi CHI Zhe LIU Chenguang 
funded by the Shandong Provincial Key Research and Development Program(No.2019GSF107031).
Sulfated polysaccharides extracted from seaweeds,including Carrageenan,Fucoidan and Ulvan,are crucial bioactive compounds known for their diverse beneficial properties,such as anti-inflammatory,antitumor,immunomodulat...
关键词：SEAWEED sulfated polysaccharides HYDROGELS biomaterials in medical applications 
Anti-obesity effects of fucoidan from Sargassum thunbergii in adipocytes and high fat diet induced obese mice through inhibiting adipogenic specific transcription factor
《Food Science and Human Wellness》2024年第3期1608-1616,共9页Hyo-Geun Lee H.H.A.C.K.Jayawardhana Fengqi Yang D.P.Nagahawaththa N.M.Liyanage Kyung-Mo Song Yun-Sang Choi Seung-Hong Lee You-Jin Jeon Min-Cheol Kang 
The“Basic Science Research Program”extended its support via the National Research Foundation of Korea (NRF),which is sponsored through the Ministry of Education (2018R1C1B6004780);supported by Main Research Program (E0211200-03)of the Korea Food Research Institute (KFRI)funded by the Ministry of Science and ICT。
The prevalence of obesity has increased and is a health concern worldwide.Due to the concerns regarding synthetic anti-obesity treatments,nowadays natural products become a trend.Previous studies proved that there is ...
关键词：Sargassum thunbergii FUCOIDAN ANTI-OBESITY Anti-steatosis 
Low-molecular-weight fucoidan inhibits the proliferation of melanoma via Bcl-2 phosphorylation and PTEN/AKT pathway
《Oncology Research》2024年第2期273-282,共10页MINJI PARK CHULHWAN BANG WON-SOO YUN YUN-MI JEONG 
supported by the Priority Research Centers Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Education,Science and Technology(Grant 2017R1A6A03015562 and RS-2023-00237386).
Fucoidan,a sulfate polysaccharide obtained from brown seaweed,has various bioactive properties,including anti-inflammatory,anti-cancer,anti-viral,anti-oxidant,anti-coagulant,anti-thrombotic,anti-angiogenic,and anti-He...
关键词：Low-molecular-weight fucoidan MELANOMA Patient-derived melanoma explants in a 3D-printed collagen scaffold Anti-melanoma effect PTEN-AKT-Bcl-2 network 
Polyelectrolyte Complexes between Hyperbranched and Linear Polysaccharides: Fucoidan/Chitosan
《Chinese Journal of Polymer Science》2024年第4期468-479,共12页Ekaterina R.Gasilova Daria N.Poshina Aleksandra O.Sitnikova Natalia N.Saprykina Yury A.Skorik 
jointly funded by the Russian Science Foundation;the St.-Petersburg Science Foundation(No.23-23-10005)
Polyelectrolyte complexes(PECs)of hyperbranched(HB)and linear polysaccharides are promising as more effective encapsulation agents compared to PECs formed by linear polysaccharides.We investigated the PECs between the...
关键词：Polyelectrolyte complexes CHITOSAN Hyperbranched fucoidan Light scattering 
Cartilage-inspired self-assembly glycopeptide hydrogels for cartilage regeneration via ROS scavenging被引量：1
《Bioactive Materials》2024年第2期319-332,共14页Zhijian Zhao Xiaowei Xia Junlin Liu Mingzhuang Hou Yang Liu Zhangzhe Zhou Yong Xu Fan He Huilin Yang Yijian Zhang Changshun Ruan Xuesong Zhu 
supported by grants from National Key R&D Program of China(Grant Nos:2022YFC2502902);National Natural Science Foundation of China(Grant Nos:82072442,82272494,82072082 and 32122046);the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD);the Shenzhen Fundamental Research Foundation(Grant Nos.JCYJ20210324115814040 and JCYJ20210324113001005).
Cartilage injury represents a frequent dilemma in clinical practice owing to its inherently limited self-renewal capacity.Biomimetic strategy-based engineered biomaterial,capable of coordinated regulation for cellular...
关键词：Cartilage repair Self-assembly glycopeptide hydrogels FUCOIDAN ROS scavenging 
Fucoidan Ameliorates Ferroptosis in Ischemia-reperfusion-induced Liver Injury through Nrf2/HO-1/GPX4 Activation被引量：3
《Journal of Clinical and Translational Hepatology》2023年第6期1341-1354,共14页Jing-Jing Li Wei-Qi Dai Wen-Hui Mo Wen-Qiang Xu Yue-Yue Li Chuan-Yong Guo Xuan-Fu Xu 
supported by the National Natural Science Foundation of China(No.82100638,81772591);Shanghai Municipal Commission of Health and Family Planning(No.201740156);the Shanghai Sailing Program(No.20YF1443300).
Background and Aims:Liver ischemia-reperfusion(IR)injury is a common pathological process in liver surgery.Ferroptosis,which is closely related to lipid peroxidation,has recently been confirmed to be involved in the p...
关键词：FUCOIDAN ISCHEMIA-REPERFUSION Ferroptosis Lipid peroxidation NRF2 
Fucoidan sulfate from Sargassum fusiforme regulates the SARS-CoV-2 receptor AXL expression in human embryonic lung diploid fibroblast cells
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2023年第11期1047-1052,共6页Xuqiang ZHOU Weihua JIN Di JIANG Yipeng XU Sanying WANG Xinna WU Yunchuang CHANG Huili SU Tianjun ZHU Xiaogang XU Genxiang MAO 
supported by the Chinese Traditional Medicine Science and Technology Projects of Zhejiang Province (Nos.2021ZB002,2022ZB002,and 2020ZQ002);the National Natural Science Foundation of China (No.31702144);the Zhejiang Province Basic Public Welfare Research Project (No.LGF21H250002);the National Administration of Traditional Chinese Medicine and Zhejiang Province (No.GZY-ZJ-KJ-24001),China.
Coronavirus disease 2019(COVID-19)is a global infectious disease that seriously endangers human life and health and affects normal social activities.Since the pandemic outbreak from December 2019 to February 2023,the ...
关键词：SARGASSUM LUNG cases 
Pharmacokinetics of fucoidan and low molecular weight fucoidan from Saccharina japonica after oral administration to mice
《Journal of Oceanology and Limnology》2023年第5期1900-1909,共10页Jiaojiao TAN Yimin SONG Jing WANG Ning WU Yang YUE Quanbin ZHANG 
Supported by the National Natural Science Foundation of China (Nos.42176137,81872906);the Nantong Science and Technology Project (No.MS12021037);the STS Program of Chinese Academy of Sciences (No.KFJ-STS-QYZD-195);the K.C.Wong Education Foundation;CAS。
The brown seaweed,Sacchairna japonica,has been used in traditional Chinese medicine for over one thousand years.Oral administration of fucoidan or low molecular weight fucoidan(LMWF)from S.japonica could ameliorate ki...
关键词：FUCOIDAN low molecular weight fucoidan PHARMACOKINETICS BIOAVAILABILITY tissue distribution 
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