肿瘤热疗中热剂量的应用与研究现状  

Current status of application and research of thermal dosimetry in tumor hyperthermia

作　　者：雷锋林[1] 夏启胜(综述)[1,2] 赵凌云[2] 唐劲天(审校)[1,2] 

机构地区：[1]北京中医药大学生物制药系,100102 [2]中日友好医院临床医学研究所肿瘤学分子生物学研究室

出　　处：《国际肿瘤学杂志》2008年第11期832-835,共4页Journal of International Oncology

摘　　要：热剂量作为肿瘤热疗治疗效果的一种评价方法，其测量指标及参数的研究是热疗治疗系统的关键内容。基础研究发现热剂量学在研究热生物学损伤与热暴露（温度和时间）的关系中起主导作用。随着热剂量学研究的进一步深入，热剂量学的相关原理、热剂量参数及其模型有望全面而准确的表达热疗效果，使临床经验及热疗处方更加完善。热剂量学的广泛应用和深入研究将使肿瘤热疗技术更加规范。As a quantitative evaluation approach for tumor hyperthermia, thermal dosimetry is a critical part of the treatment planning system and plays a key role in governing the relationships between thermal exposure （temperature and time of exposure ） and thermal damage. Its principal theories, parameters as well as thermal dosimetl3, models are potentially to accurately describe the tumor hyperthermia effectiveness and therefore greatly improve the clinical experience and prescription for tumor hyperthermia. The deep study and wide clinical application of thermal dosimetry in hyperthermia will further standardize tumor hyperthermia and benefit the patients more.

关 键 词：肿瘤 温度 时间 

分 类 号：R730[医药卫生—肿瘤]