幽门螺杆菌感染在慢性胃炎患者中的危险因素  

Risk factors for helicobacter pylori infection in patients with chronic gastritis

作　　者：苏爱平[1] 许翠萍[2] 房晓芬[2] 王建春[2] 张太新[2] 

机构地区：[1]山西医科大学,山西省太原市030001 [2]山西医科大学第一医院消化内科,山西省太原市030001

出　　处：《世界华人消化杂志》2008年第33期3810-3813,共4页World Chinese Journal of Digestology

摘　　要：目的:探讨慢性胃炎患者幽门螺杆菌(H pylori)感染的危险因素.方法:对345例经胃镜确诊的慢性胃炎患者采用统一调查表进行问卷调查,14C-尿素呼气试验检查H pylori,H pylori阳性191例列为病例组,H pylori阴性154例列为对照组.结果:单因素分析显示文化程度、居住地、在外就餐、进餐速度、暴饮暴食、食醋、食用辛辣食物、食用油炸食品、胃病家族史、精神紧张与H pylori感染的关系有统计学意义(P<0.05).多因素分析表明文化程度、在外就餐、暴饮暴食、食醋及食用辛辣食物5个因素有显著性差异.其中,文化程度、食醋与H pylori感染呈负相关(β=-0.247,-0.510,均P<0.05),外出就餐、暴饮暴食、食用辛辣食物与H pylori感染呈正相关(β=0.617,0.577,0.190,均P<0.05).结论:经常在外进餐、暴饮暴食及食用辛辣食物可显著增加H pylori感染的危险性,提高文化程度,适量食醋可以减少H pylori感染的风险.AIM：To investigate the risk factors for H pylori infection in patients with chronic gastritis.METHODS：A total of 345 cases with chronic gastritis confirmed by gastroscopy completed a unified questionnaire survey.H pylori infec-tion was assessed using the 14C-urea breath test.The 191 H pylori-positive cases were taken as case group while the 154 H pylori-negative cases were taken as control group.The univariable and multivariable analyses were carried out us-ing the Chi-Square Tests and Logistic regression method.RESULTS：Single factor analysis showed that the H pylori infection was related to educational background,living areas,eating outside,eating speed,engorgement,vinegar use,preference of spicy food,food fried in oil,family history andmental stress（all P〈0.05）.The multivariable un-conditional Logistic regression analysis showed that the H pylori infection was related signifi-cantly to the educational background,eating outside,engorgement,vinegar and preference of spicy food.H pylori infection was negatively associated with the educational background and vinegar use（β=-0.247,-0.510,both P〈0.05）,but positively associated with eating outside,engorgement and preference of spicy food（β= 0.617,0.577,0.190,all P〈0.05）.CONCLUSION：Eating outside frequently,en-gorgement and preference of spicy food increase the risk for H pylori infection,while increased d education and proper vinegar use decrease the risk for H pylori infection.

关 键 词：慢性胃炎 幽门螺杆菌 危险因素 

分 类 号：R573.3[医药卫生—消化系统]