氩氦刀冷冻治疗早期肝癌疗效分析  

Treatment of early-stage hepatocellular carcinoma with argon-helium cryosurgical ablation system

作　　者：周霖[1,2] 杨永平[2] 刘静[3] 冯永毅 陆荫英[2] 王春平[2] 王新真[2] 安林静[2] 张昕[2] 郝丽燕[2] 王福生[2] 

机构地区：[1]军医进修学院学员队,北京100853 [2]解放军第302医院 [3]北京海军总医院

出　　处：《胃肠病学和肝病学杂志》2008年第12期1000-1002,共3页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的通过回顾性分析,评价氩氦刀冷冻治疗早期肝癌的临床疗效。方法选择48例经氩氦刀冷冻治疗的早期肝癌患者,以治疗后患者的临床表现、局部病灶CT变化、AFP下降情况、术后并发症的发生及平均生存时间作为评价指标。结果氩氦刀冷冻治疗肝癌后患者的并发症少,本研究结束后,共有23例患者存活,25例患者死亡。中位生存期为(33.91±1.39)个月,1、2、3、4年生存率分别为81.3%、62.1%、47.6%、44.4%。结论对于合并严重肝硬化的早期肝癌,氩氦刀治疗的并发症少、效果明显、生存期延长,是理想的治疗手段。Objective To evaluate the clinical effect of argon-helium cryosurgical ablation system to treat early-stage hepatocellular carcinoma. Methods Totally 48 early-stage hepatocellular carcinoma patients were treated. Clinical symptom, tumor size, AFP, complications and survival time were analysised. Results At the end of the study, 23 pa- tients survived and 25 patients died. Survival time was （33.91 ± 1.39）month, survival rates of 1, 2, 3, 4 year were 81.3% , 62. 1% , 47.6% and 44.4% , respectively. Conclusion To early-stage hepatocellular carcinoma patients with severe liver cirrhosis, argon-helium cryosurgical ablation therapy is a ideal alternative with the advantage of few complications and good outcome.

关 键 词：原发性肝癌 早期 冷冻治疗 生存时间 

分 类 号：R735.7[医药卫生—肿瘤]