盐酸甲氯芬酯在急性脑出血中的临床应用疗效观察  

Meclofenoxate Hydrochloride in Patients with Acute Cerebral Hemorrhage in the Clinical Efficacy Observation

作　　者：吕新华[1] 颜建辉[1] 黄克敏[1] 

机构地区：[1]湘南学院附属医院神经内科,湖南郴州423000

出　　处：《湘南学院学报（医学版）》2008年第4期7-8,12,共3页Journal of Xiangnan University（Medical Sciences）

摘　　要：目的观察盐酸甲氯芬酯治疗急性脑出血临床病例疗效。方法将62例脑出血患者进行随机均分治疗组和对照组。对照组用常规治疗方法,治疗组在常规治疗的基础上,加用盐酸甲氯芬酯0.5g,静脉滴注,每日1次,共4周。于治疗前及治疗后第4周后分别进行神经功能缺损评分及疗效评定。结果治疗4周后,治疗组神经功能缺损评为(9.6±6.3)分,明显低于对照组的(14.4±7.6)分(P<0.05);治疗组的显效率和有效率分别为61.29%和87.10%,显著高于对照组的38.71%和54.85%(P<0.05)。结论盐酸甲氯芬酯可促进脑出血患者的神经功能保护和康复作用。Objective To evaluate the efficacy of hydrochloric acid meclofenoxate on the treatment of acute cerebral hemorrhage.Methods Sixty- two cases were divided into treatment group and control group randomly. Necurological fimctional defieitscores were utilized for assessment before given treatment, on the 4 weeks after treatment, the patient was assessed again and the efficacy was recordsd. Results After 4 weeks treatment, the neurological functional deficit scores of treated group were 9.6 ± 6.3, whereas those of the control group were 14. 4 ± 7.6. There was significant difference between the two groups （ P 〈 0.05）. There were also significant differenceds between the two groups in terns of apparmt effect rote（treated group 61.29% ,control group 38.71% P 〈 0.05） and improvement rote （ treated group 87.10%, control group 54.85 % ; P 〈 0.05 ）. Conclusion Hydrochloric acid meclofenoxate can accelerate the recovery of neural function after cerebral hemorrhage.

关 键 词：脑出血 盐酸甲氯芬酯 临床应用 疗效观察 

分 类 号：R743.34[医药卫生—神经病学与精神病学]