肝内胆管癌与肝细胞癌免疫组化差异对比分析  

ANALYSIS OF THE IMMUNOHISTOCHEMICAL DIFFERENCE BETWEEN THE INTRAHEPATIC CHOLANGIOCARCINOMA AND HEPATIC CELL ARCINOMA

作　　者：宗华[1] 宗明[2] 

机构地区：[1]河南省焦作市人民医院,焦作454001 [2]东方肝胆外科医院

出　　处：《肝胆外科杂志》2008年第6期466-467,共2页Journal of Hepatobiliary Surgery

摘　　要：目的统计、对比、分析肝内胆管癌(Intrahepatic Cholangiocarcinoma,ICC)及肝细胞癌(Hepatic Cell Carcinoma,HCC)免疫组化差异。方法术后病理诊断ICC患者810例作为研究组,随机抽取同期HCC患者810例作为对照组(肝门部胆管癌不在本次研究之列);收集免疫组化资料用SPSS12.0软件统计,行χ2检验或Fisher′s检验。结果统计结果显示:ICC和HCC两组在Hep-1、HbsAg、CK19、CD34、P53、PCEA、CA19-9、HER-2、MUC1、CD10、AQP-1有显著差异(P<0.05)。结论ICC是原发性肝癌(Primary Liver Cancer,PLC)的一种特殊类型,其免疫组化特征与HCC有明显差异。Objective This study aimed to statistiesing, contrasting and analyzing the immunohistoehemical difference between ICC and HCC. Methods The immunohistochemieal data of 810 cases with ICC （excepting the Klatskin＇s tumor）,which were diagnosed by the postoperative pathology ,were respectively collected and compared with those of 810 HCC cases in the same period, and there werel9 data which were selected and collected for χ^2 and Fisher＇s analysis by SPSS12. 0 statiscal software. Results The analysis （ revealed that there were significant immunohistochemical difference between ICC and HCC in Hep-1、 HbsAg, CK19、 CD34、P53 PCEA、CA19-9、HER-2、MUC1,CD10、AQP-1 （P 〈 0. 05 ）. Conclusion ICC were a specific kind of PLC, and the immunohistochemical difference between ICC and HCC is significance.

关 键 词：肝内胆管癌 肝细胞性肝癌 免疫组织化学 差异 

分 类 号：R735.7[医药卫生—肿瘤]