放射加博宁治疗骨转移癌的病例分析  

Analysis of the therapeutic effect for 100 cases bone metastases

作　　者：郭汝涛[1] 郝春成[1] 李香兰[1] 葛晓峰[1] 

机构地区：[1]哈尔滨医科大学第三附属医院,黑龙江哈尔滨150040

出　　处：《现代生物医学进展》2008年第11期2084-2085,共2页Progress in Modern Biomedicine

摘　　要：目的:观察放疗和博宁对骨转移癌的止痛效果。方法:对100例骨转移癌患者进行回顾性分析,单纯放疗30例,博宁加放疗14例,博宁加放化疗56例。结果:全组总有效率为89%,显效率达51%。各组有效率:单放组为83-3%,博宁加放疗组为92.9%,博宁加放化组为91.1%。三组间止痛效果无显著性差异(P>0.05)。在应用博宁治疗组中有一例出现类似过敏反应症状,其他无明显毒副反应发生。结论:放射治疗骨转移癌止痛迅速而有效。博宁治疗骨转移癌止痛效果明显,尤其适合应用于多发性骨转移癌患者。二者联合应用效果更加。Objective：To evaluate the therapeutic effect of Radiotherapy and Bonin （Disodiun Pamidronate） on bone metastases. Methods：100 cases were retrospectively analyzed,in which radiotherapy were 30 cases,Bonin with radiotherapy 14 cases and Bonin with chemotherapy and radiotherapy 56 cases.Results：The overall effective rate of Bonin for bone pain in the 100 patients with bone metastases was 89%,and the complete response was 51%.As compared to the efficacy of 83.3% in the radiotherapy alone group,the combination group of Bonin with radiotherapy got an efficacy of 92.9% and the combination group of Bonin with chemotherapy and radiotherapy,91.1%.The differences were not statistically significant （P〉0.05）.It had few and slight side-effect.Conclusion：Radiotherapy has a good and quick therapeutic effect for bone metastases.Bonin is an effective drug and could be used in patients with bone metastases in combination with radiotherapy and chemotherapy.

关 键 词：骨转移癌 放射治疗 博宁 

分 类 号：R738.1[医药卫生—肿瘤]