瑞美隆治疗抑郁症临床对照研究  

Clinical study of Remeron on patients with depression

作　　者：刘伟伟 

机构地区：[1]郑州市第八人民医院,郑州450000

出　　处：《中国实用神经疾病杂志》2008年第12期52-53,共2页Chinese Journal of Practical Nervous Diseases

摘　　要：目的采用随机方法评价瑞美隆对于抑郁症的临床疗效。方法入选98例病人,随机分为治疗组50例和对照组48例,2组病人的一般情况及病情程度等具有可比性。对照组给予多虑平片50mg,2次/d,疗程8周;治疗组给予瑞美隆片30mg,1次/d,疗程8周。8周后观察临床疗效及不良反应。采用汉密尔顿抑郁量表(HAMD)和汉密尔顿焦虑量表(HAMA)评定疗效,以TESS评价安全性。结果治疗组疗效明显优于对照组,不良反应发生率低。结论瑞美隆具有较好的抗抑郁作用,且不良反应少。Objective To observe the clinical effect of Remeron on patients with depression. Methods In randomized trial, we took 50 patients with depression as treatment group, 48 patients in control group. There was no statistical difference between two groups in state of disease and general condition etc. For control group,Doxepin （oral dosage, 25 mg, twice a day） and Remeron（30 rag, daily ） were given. After 8 weeks of treatment,based on depression scale of HAMD and HAMA,observation was given. Results Treatment group had better clinical effect than control group with low side effect incidence. Conclusion With low side effect incidence and perfect security,Remeron has better clinical effect on patients with depression.

关 键 词：抑郁症 瑞美隆 多虑平 

分 类 号：R749.41[医药卫生—神经病学与精神病学]