药物自我管理技能训练对女性首发精神分裂症患者的影响  

Effect of medicine self-control skill training on first-episode female schizophrenic patients

作　　者：袁金莲 程家蓉[1] 李洪毅[1] 吴琳琳[1] 

机构地区：[1]四川省攀枝花市第三人民医院,617061

出　　处：《检验医学与临床》2009年第1期5-6,8,共3页Laboratory Medicine and Clinic

摘　　要：目的探讨药物自我管理技能训练对女性首发精神分裂症患者的影响。方法选取首发精神分裂症患者84例,在入院时将患者随机分为两组,对照组进行常规护理,观察组增加药物的自我管理技能训练。采用简明精神病评定量表(BPRS)[1]、自知力与治疗态度问卷量表(ITAQ)[2]以及自编服药依从性评定调查表,分别在患者出院时、出院半年及1年后进行评分及资料收集。结果两组患者在出院时BPRS评分相当,对照组为(21.78±3.17)分,观察组为(20.36±3.08)分;但观察组在出院半年或1年时,BPRS评分明显低于对照组,出院半年时分别为(31.75±4.62)、(23.67±4.25)分,出院1年时分别为(36.58±4.84)、(27.34±4.01)分(P<0.05);观察组的ITAQ评分在出院时、出院后半年、1年均明显高于对照组,差异有统计学意义(P<0.05),分别是(11.97±2.53)、(16.02±2.78)、(10.23±3.76)、(15.34±3.42)、(9.23±3.43)、(14.72±3.11)分;观察组出院后半年至1年服药依从性较对照组明显提高,差异有统计学意义(P<0.05);从患者出院半年、1年内复发率看,观察组明显低于对照组,差异有统计学意义(P<0.05)。结论药物的自我管理技能训练提高了患者服药治疗的依从性,对预防复发、改善预后有一定作用。Objective To study the effect of medicine self-control skill training on first-episode female schizophrenic patients. Methods Eighty-four female first-episode schizophrenics were randomly divided into control group （receiving usual care） and observation group （besides usual care, medicine self-control skill training was given） on admission. Brief Psychiatric Rating Scale （BPRS）, Insight and Treatment Attitude Questionnaire （ITAQ） and selfmade medication compliance evaluating sheet were adopted to grade the illness on admission, half a year, and one year after discharge,and the data was collected. Results The patients in control group and observation group had the similar BPRS score at discharge （21.78±3.17 vs 20.36±3.08） ; nevertheless,the patients in observation group had significantly lower scores than those in control group half a year and one year after discharge （23.67± 4.25 vs 31.75 ± 4.62; 27.34 ± 4.01 vs 36.58±4.84, respectively）. ITAQ scores in observation were significantly higher than those in control group at discharge,half a year and one year after discharge （16.02±2.78 vs 11.97±2. 53; 15.34±3.42 vs 10.23 ±3.76; 14.72 ± 3.11 vs 9.23 ± 3.43, respectively, all P〈0.05）. The recurrence rate was significantly lower in observation group than control group half a year and one year after discharge （P〈0.05）. Conclusion The skills training of the drug self-management can improve the medication compliance and prognosis.

关 键 词：精神分裂症 健康教育 维持治疗 自我管理 

分 类 号：R749.3[医药卫生—神经病学与精神病学]