MRI对伽玛刀治疗原发性颅内淋巴瘤的疗效评估  

To assess the role the gamma knife radiosurgery in the treatment of the primary intracranial lymphoma by MRI.

作　　者：邓珍萍[1] 费红英 任鸿萍 廖述才 原珍团[1] 张晓鸽[1] 鲁宏[1] 

机构地区：[1]成都市第二人民医院影像科,四川成都610017 [2]成都市航天医院影像科,四川成都610100 [3]成都市363医院伽玛中心,四川成都610041

出　　处：《四川医学》2008年第12期1712-1713,共2页Sichuan Medical Journal

摘　　要：目的应用MRI评估7刀治疗原发性颅内淋巴瘤的治疗效果。方法回顾性分析经病理证实的7例颅内淋巴瘤，γ刀治疗后随访6个月-3年，对其γ刀治疗前后的MRI平扫及增强资料进行分析。结果4例系幕上及幕下多发瘤灶，3例系幕上单发瘤灶，MRI平扫T1WI瘤灶呈较低信号或等信号，T2WI呈等信号或稍高信号，GD-DTPA增强后呈明显均匀强化。肿瘤灶周水肿较轻。γ刀治疗后5例瘤灶消失，2例瘤灶明显缩小，灶周水肿均明显消退。结论颅内淋巴瘤的MRI影像表现有较强特征性，是该肿瘤伽玛刀治疗疗效评价的最理想的影像学检查方法。Objective To review MRI feature of primary intraeerebral malignant lymphoma（PICML） and to assess the role of the gamma knife radiosurgery in the treatment of PICML by MRI. Methods Seven patients with pathology proven PICML were treated with gamma knife radiosurgery and were followed up for 6 - 36 months. To review MRI feature of PICML retrospectively, through contrasted and uon-contrasted images pre- and post- gamma knife fadiosurgery. Results 4 patients have multiple lesions and single-lesion was found in 3 patients;The MRI findings of PICML were as follow ：hypo- or iso-intense on TIWI and iso- or slishfly hyper-intense of T2WI, slight or moderate peritumoral edema, enhancement is intense and homogeneous. After the gamma knife radiosurgery, 5 lesions were disappeared,2 lesions were reduced obviously from size and edema. Conclusion PICML is characteristic in MRI,MRI is a most effective way to assess the role of the gamma knife radiosurgery in the treatment of PICML.

关 键 词：颅内淋巴瘸 磁共振成像 Γ刀 

分 类 号：R739.41[医药卫生—肿瘤]