缺血性脑血管病潜在的新危险因素  

New Potential Risk Factors for Ischemic Stroke

作　　者：郭瑞友[1] 王彩霞[1] 刘前[1] 

机构地区：[1]青岛市青岛大学医学院附属海慈医院神经内科

出　　处：《医学综述》2009年第1期84-87,共4页Medical Recapitulate

摘　　要：缺血性卒中已明确的危险因素有高血压、高胆固醇血症、颈动脉狭窄、吸烟、糖尿病、缺血性或瓣膜性心脏病等。随着对卒中研究的不断深入，发现了许多潜在的新危险因素如：ApoB—ApoAⅠ比率升高、腹部肥胖、C反应蛋白增高、高同型半胱氨酸血症、高屎酸血症、遗传易感性、睡眠呼吸暂停、微量白蛋白尿、感染、药物滥用等。但要确定它们是否为缺血性脑血管病真正的危险因素，尚需要降低这些危险因素可显著降低脑血管病发病率的循证医学的证据。本文综述国际上有关该领域研究的最新进展。Hypertension high blood cholesterol carotid stenosis atrial fibrillation cigarette smoking diabetes mellitus and ischemie heart diseases are causal risk factors for ischemic stroke. Some potential new risk factors for ischemic stroke have been advanced in recent years, such as raised ApoB-ApoA1 ratio ,abdominal obesity,high-sensitivity C-reactive protein,uric acid,great homocysteine,inherited susceptibility,obstructive sleep apnea,microalbuminuria infection,drug abuse et al. However,their causal role remains to be proven ,it has not been shown in randomized controlled trials that reducing exposure to these risk factors reduces the risk of stroke.

关 键 词：缺血性脑卒中 危险因素 病因 

分 类 号：R743[医药卫生—神经病学与精神病学]