中药色谱指纹图谱相似度评价新模型及其论证  

Study of a new method on similarity evaluation for chromatographic fingerprint as applied in traditional Chinese medicine

作　　者：谷瑞敏[1] 郭治昕[2] 刘巍巍[2] 孙鹤[1] 

机构地区：[1]天津大学药物科学与技术学院,天津300072 [2]天士力集团研究院,天津300402

出　　处：《中成药》2009年第1期1-4,共4页Chinese Traditional Patent Medicine

摘　　要：目的:为进一步发展和完善用于中药质量评价的色谱指纹图谱相似度计算方法。方法:应用了中药实例研究数据和模拟数据对已有和新提出的图谱相似度计算法各自特点进行了比较和分析。结果:表明新提出的图谱相似度计算新模型在实践应用中具有很多优势。结论:在实际应用中,新模型自身固有的模型特点对中药质量评价和控制的解释更具合理性和实用性。AIM： To develop and perfect the similarity algorithm on chromatographic fingerprints of traditional Chinese medicine （TCM）. METHODS： The experimental and simulated data were used to investigate and verify the characteristics on the new and former methods on similarity evaluation for chromatographic fingerprints method. RESULTS： There are many strong points for new similarity algorithm in practice. CONCLUSION： The new method provides more rationality and practicability in TCM quality control and analysis compare to existing methods.

关 键 词：中药 色谱指纹图谱 相似度评价 质量控制 

分 类 号：R284.1[医药卫生—中药学]