派丽奥软膏治疗固定义齿修复后再发牙周炎的疗效观察  

Clinical efficacy of periocline ointment in recurrent periodontitis after fixed denture repair

作　　者：詹春华[1] 刘冰[1] 陆笑[1] 翁春辉[1] 

机构地区：[1]暨南大学附属第四医学院广州市红十字会医院口腔科,广东广州510220

出　　处：《广东医学院学报》2008年第6期604-605,608,共3页Journal of Guangdong Medical College

摘　　要：目的观察派丽奥(米诺环素)软膏治疗固定义齿修复后再发牙周炎的疗效。方法选择自身配对固定义齿修复后再发慢性牙周炎患者48例共96颗牙,随机分成派丽奥组(n=48)和碘甘油组(n=48),观察8周后临床症状、牙周袋探诊深度(PD)、菌斑指数(PLI)、龈沟出血指数(SBI)改变。结果派丽奥组总有效率(76.4%)明显优于碘甘油组(45.1%)(P<0.01),PD、SBI、PLI值均比碘甘油组低(P<0.01)。结论派丽奥软膏治疗固定义齿修复后再发牙周炎有明显疗效。Objective To observe the therapeutic effect of periocline （minocycline） ointment on recurrent periodontitis after fixed denture repair. Methods Self-controlled 48 patients （96 teeth） with recurrent periodontitis after fixed denture repair were randomly divided into two groups： periocline group （ n = 48） and iodine glycerine group （ n = 48）. Clinical manifestation, periodontal pocket （PD）, plaque index （PLI） and sulcular bleeding index （SBI） were recorded after 8 weeks. Results The total effective rate in periocline group was superior to that in iodine glycerine group （76.4% vs 45.1%, P〈0.0I）. PD, PLI and SB1 in periodine group decreased obviously as compared with iodine glycerine group （P 〈 0.01）. Conclusion Periocline ointment is effective for lreating recurrent periodontitis after fixed denture repair.

关 键 词：牙周炎 派丽奥 碘甘油 固定义齿 

分 类 号：R781.4[医药卫生—口腔医学]