多壁碳纳米管对微量苯二氮卓类药物的吸附性能研究  

Adsorption Performance of Multi-walled Carbon Nanotubes to Trace Benzodiazepines

作　　者：汪丽萍[1] 赵海香[2] 邱月明[3] 

机构地区：[1]国家粮食局科学研究院,北京100037 [2]河北北方学院,张家口075131 [3]中国标准化研究院,北京100088

出　　处：《分析化学》2009年第1期77-81,共5页Chinese Journal of Analytical Chemistry

基　　金："十五"国家重大科技专项"食品安全关键技术"子课题"兽药残留检测技术研究"(No.2001BA804A18)资助项目

摘　　要：研究了静态吸附条件下多壁碳纳米管(MWCNTs)对地西泮、艾司唑仑、阿普唑仑和三唑仑4种苯二氮卓类药物的吸附性能,10min内能达到吸附平衡。MWCNTs对药物的吸附容量随药物浓度的增加而增加,最小初始浓度时MWCNTs对4种药物的静态吸附容量分别为7.95、7.88、7.99和7.73mg/g,吸附容量较大。295、303和313K温度下的吸附实验表明,吸附容量随温度的升高而减小,降低温度有利于药物的吸附。对不同温度下的吸附等温线采用Freundlich和Langmuir方程进行拟合,结果显示Langmuir方程具有更好的拟合效果。在动态吸附条件下穿透体积的测定显示MWCNTs对药物也具有大的吸附容量且萃取回收率高达90%以上。The adsorption performance of MWCNTs to four benzodiazepines including diazepam, estazolam, alprazolam and triazolam was examined. Four drugs can be adsorbed rapidly and quantitatively on MWCNTs in the static adsorption experiment, and the adsorption equilibrium was obtained within 10 min. The adsorptive capacities of MWCNTs increase with increasing concentration of these drugs. In original drugs concentration, the adsorptive capacities of MWCNTs to four drugs were greater. The adsorptive capacity was 7.95, 7.88, 7.99 and 7.73 mg/g, respectively. The effects of experimental temperature were studied at 295 K, 303 K and 313 K. The adsorptive capacities of MWCNTs increased while temperature dropped. The data were simulated by Freundlich and Langmuir equations. The Langmuir equation accorded with the tic of the compounds. The data from the dynamic adsorption experiment showed and the extraction recoveries of four drugs on MWCNTs were satisfactory. The drugs were more than 90%. The results indicated that MWCNTs could be used the determination of benzodiazepines residues. static adsorption characteristhat the adsorption capacity extraction recoveries of four as a solid phase sorbents for the determination of benzodiazepines residues.

关 键 词：多壁碳纳米管 苯二氮卓 吸附 

分 类 号：R155.5[医药卫生—营养与食品卫生学]