47例肝脏占位性病变患者肝脏病理检查与血生化联合检测的对比研究  

Comparative study between Pathological Results of Liver Biopsy and Serumal Index in 47 cases with liver occupying lesions

作　　者：刘军英[1] 苏毅[1] 陈应华[1] 

机构地区：[1]贵州省遵义市遵义医学院第一附属医院,遵义563003

出　　处：《临床内科杂志》2009年第1期30-31,共2页Journal of Clinical Internal Medicine

摘　　要：目的评价肝脏活组织病理检查对早期诊断原发性肝癌的临床价值及其与血清甲胎蛋白（AFP）、碱性磷酸酶（AKP）、γ-谷氨酰转移酶（GGT）指标和影像学的相关性，以提高原发性肝癌的早期诊断率。方法对47例影像学检查提示肝脏占位性病变并进行肝活检患者进行回顾性分析。结果临庆诊断为原发性肝癌的患者47例，病理检查证实28例，临床诊断与病理检查符合率为59．60％，1例外科手术切除前肝活检未查见癌细胞的患者，术后证实为胎儿型肝母细胞瘤，有2例做肝活检2次，有2例做肝活检3次而查见癌细胞。结论肝活检是诊断原发性肝癌的金标准，但在临床应用过程中存在客观误差，需多次多部位多方向取材，并结合血生化指标及影像学检查，以提高早期肝癌的诊断率。Objective To study the correlation between clinical value of liver biopsy and serumalAFP ,AKP, GGT index and imageology for elevating early diagnosis of primary hepatic carcinoma（ PHC ）. Methods A total of 47 patients with mass screening detected by liver iconography received liver punctios and were retrospectively analyzed. Results Of 47 pacients,28 were confirmed the primary hepatic carcinoma by pathology. Coincidence between clinical and pathological diagnosis is 59.60% （ 28/47 ）. Cancer cells were not checked out in liver biopsy before tumorectomy,while checked out by pathology after operation. Two patients received twice liver punctios,two patients received three times. Conclutions Although liver biopsy is ＂Gohlen index＂ for diagnosing PHC, the relative accuracies rely on both clinical and pathol- ogy examinations. Early diagnosis of PHC with liver punctio needs to take multiple-spot-aspect means and combined with seramal index and imageology examinations.

关 键 词：肝活检 肝癌 

分 类 号：R735.7[医药卫生—肿瘤]