羧酸硒醚、二硒醚及相应硒多糖的合成  

Syntheses of Carboxylic Selenides,Diselenides and Their Seleno-polysaccharides

作　　者：林晓芝[1,2] 黎永铭[1] 唐渝[1] 

机构地区：[1]暨南大学化学系,广东广州510632 [2]汕头职业技术学院自然科学系,广东汕头515000

出　　处：《化学世界》2009年第1期40-43,53,共5页Chemical World

基　　金：广东省自然科学基金团队项目资助(039213)

摘　　要：用NaBH4还原硒粉得Se^2-或^-SeSe^-，然后在碱性水溶液中与氯乙酸、3-氯丙酸和对-溴甲基苯甲酸在室温下反应，制得相应的羧酸硒醚，收率分别为51．9％、62．6％和58．6％，以及丙酸和对甲基苯甲酸二硒醚，收率67．8％和72．1％。用乙酸硒醚分别与邻氨基苯甲酸和水杨酸反应引入其他基团，收率73．6％和69．8%。最后这些合成的化合物通过形成酰氯与麒麟菜多糖中的羟基醚化得到含硒醚或二硒醚结构的新型硒多糖，收率40％～60％。Se^2- or ^-SeSe^- was formed by reduction selenides with yields of 51.9%, 62.6% and 58.6%, of selenium with NaBH4. Corresponding carboxylic as well as propionic and p-methyl benzoic diselenides with yields of 67. 8% and 72. 1% were synthesized by reacting Se^2- or ^-SeSe^- with chloroaeetic, 3- ehoropropionic and p-bromomethyl benzoic acids in alkali aqueous solution. Other groups were tried to be introduced by reacting acetic selenide with o-aminobenzoic and salicylic acids. Finally, novel selenopolysaccharides with selenide and diselenide structure were obtained by esterifying hydroxyl of polysaccharide with acyl chloride of these synthesized compounds.

关 键 词：硒醚 二硒醚 酰化反应 硒多糖 

分 类 号：O627.6[理学—有机化学]