侵及左心房和肺静脉根部肺癌的外科治疗探讨  

Surgical treatment for lung cancer invading left atrium and base of pulmonary vein

作　　者：乌立晖[1] 徐志飞[1] 赵学维[1] 李建秋[1] 孙耀昌[1] 

机构地区：[1]第二军医大学长征医院胸心外科,上海200003

出　　处：《中华肿瘤防治杂志》2008年第20期1581-1583,共3页Chinese Journal of Cancer Prevention and Treatment

摘　　要：目的:探讨扩大性外科手术治疗左心房和肺静脉受侵犯的局部晚期肺癌的疗效。方法:2000-01-01-2006-01-31对46例侵及左心房或肺静脉根部的肺癌经心包内处理肺静脉,行部分左心房切除,占同期肺癌手术的4.9%,左下肺切除术6例,左全肺切除术14例,右肺中下叶切除术8例,右肺下叶切除术2例,右全肺切除术16例。结果:本组无手术死亡,随访43例,失访3例,随访率93.5%。全组1、3、5年生存率分别为72.09%、37.50%和21.43%。结论:左心房或心包内肺静脉受侵的T4晚期肺癌,如果没有N2和N3转移,应考虑积极的手术治疗,以提高患者的生存率,并为晚期肺癌的进一步治疗创造条件。OBJECTIVE： To explore the efficacy of the extended operation for locally advanced non-small cell lung cancer invading left a trium and intrapericardial pulmonary vein. METHODS： From Jan. 2000 to Jan. 2006, lobectomy or pneumonectomy combined with extended resection of left atrium was performed in 46 patients. The operations included left low lobectomy in 6 cases, left pneumonectomy in 14 cases, right middle and low lobectomy in 8 cases, right low lobectomy in 2 cases and right pueumonectomy in 16 cases respectively, accounted for 4.9 % of patients of lung cancer who underwent surgical treatment at the same period. RESULTS： There was no surgery related mortalily. Forty-three patients were followed up. Three patients were failed in the follow up, and the follow-up rate was 93.5%. The 1-,3 and 5- year survival rates were 72.09% ,37.50% and 21.43%, respectively. CONCLUSIONS： Surgical treatment for T4 lung cancer invading the left atrium or the base of pulmonary vein is feasible, especially for N0 and N1 patients. It can improve the quality of life and increase the long term survival rates.

关 键 词：肺肿瘤/外科学 肺切除术 心房 随访研究 

分 类 号：R734.2[医药卫生—肿瘤]