肠易激综合征患者的生存质量评价及其影响因素分析  

Quality of life in irritable bowel syndrome patients and its influencing factors

作　　者：徐雪梅[1] 王巧民[1] 代子艳[1] 宋继忠[1] 

机构地区：[1]安徽医科大学附属安徽省立医院消化内科,安徽合肥230001

出　　处：《胃肠病学和肝病学杂志》2009年第1期35-37,共3页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的评价肠易激综合征(irritable bowel syndrome,IBS)病人的生存质量并分析其影响因素。方法对在消化专科门诊就诊、符合罗马Ⅲ诊断标准的73例IBS病人和78例其他功能性肠病(functional bowel diseases,FBD)患者采用肠易激综合征生存质量量表汉化版(Chinese Irritable Bowel Syndrome-Quality Of Life Questinnaires,ChIBS-QOL),以及焦虑自评量表(Self-Rating Depression Scale,SAS)、抑郁自评量表(Self-Rating Depression Scale,SDS)进行问卷调查,并建立病人的资料档案。结果ChIBS-QOL的总条目及各维度得分,尤其是饮食限制方面,均明显低于对照组(P均<0.05)。将病人的性别、年龄、婚姻状态、职业、精神心理因素、文化程度、经济收入、病程、罗马Ⅲ分型,以及是否伴随功能性消化不良(FD)作为自变量,ChIBS-QOL作为因变量,进行多元逐步回归分析,筛选出精神心理因素(β=-17.729,t=-4.506,P<0.001)和文化程度(β=3.897,t=2.688,P<0.01)是影响ChIBS-QOL总分的主要因素。结论IBS患者的生存质量明显降低,精神心理因素和文化程度是影响其生存质量的重要因素。Objective To investigate the quality of life in irritable bowel syndrome （IBS） patients and its influencing factors. Methods Seventy-three patients of IBS and seventy-eight of other functional bowel disorders （FBD） in the gastrointestinal outpatient department were diagnosed by Rome Ⅲ criteria. Chinese Irritable Bowel Syndrome-Quality Of Life Questinnaires （ChIBS-QOL） , Self-Rating Anxiety Scale （SAS） and Self-Rating Depression Scale （SDS） were self- adminstered or interview-administered to the patients. Results The ChIBS-QOL scores of eight directions and the overall score, especially in food avoidance, in IBS patients were significantly lower than those in other FBD patients （P 〈 0. 05, respectively）. Multi-factors stepwise regression analysis showed that mental status（β =-17. 729, t =- 4. 506, P 〈 0. 001 ） and the level of edueation（β = 3. 897, t = 2. 688, P 〈0.01 ） were important factors that influenced the ChIBS- QOL scores of IBS patients. Conclusion Quality of life decreases in IBS patients and its main influencing factors are mental status and the level of education.

关 键 词：肠易激综合征 生存质量 ChIBS—QOL专用量表 精神心理因素 文化程度 

分 类 号：R574[医药卫生—消化系统]