准分子激光上皮瓣下角膜磨镶术后丝状角膜病变的观察  

Observation of Filamentary Keratopathy after Excimer Laser Subepithelial Keratomileusis

作　　者：乔宝笛[1] 帖彪[1] 陈鹏[1] 

机构地区：[1]郑州市第二人民医院眼科,郑州市450000

出　　处：《医药论坛杂志》2009年第1期13-14,17,共3页Journal of Medical Forum

摘　　要：目的观察准分子激光上皮瓣下角膜磨镶术(LASEK)后丝状角膜病变的发病情况,探讨其发病相关因素及防治方法。方法将接受LASEK的263例(526眼)近视按术前有无角膜接触镜配戴史分为两组,观察术后丝状角膜病变的发生及治疗情况。结果术后发生丝状角膜病变共15例(27眼),发病率为5.13%,有角膜接触镜配戴史组及无角膜接触镜配戴史组术后丝状角膜病变的发病率分别为7.59%、3.31%,两者有显著差异(P<0.05)。丝状角膜病变的治疗可采取将丝状物剔除及使用人工泪液。结论LASEK术后丝状角膜病变发生的相关因素包括:术前角膜接触镜的配戴、术中角膜上皮层及前弹力层的损伤、术后用药等。对于术后丝状角膜病变,应采取积极的预防及处理。Objective Total To observe morbidity of filamentary keratopathy after excimer laser subepithelial keratomileusis （LASEK）. Methods Total 263 patients （ 526 eyes） treated with LASEK were divided into two groups according to having history of wearing contact lens or not, and incidences of postoperative filamentary keratopathy were compared between two groups. Filamentary keratopathy was treated, and the effect was summed up. Results Filamentary keratopathy was observed in 15 cases（27 eyes） and incidences in two groups were significantly different （P 〈 0. 05） . Treatments included removing filaments and using artificial tears. Conclusion Related pathogenesis of iliarnentary keratopathy after LASEK included wearing contact lens preoperatively, intraoperative damage to corneal epithelium and Bowman＇s membrane and using drugs postoperatively. Postoperative filamentary keratopathy should be prevented and treated actively.

关 键 词：准分子激光上皮瓣下角膜磨镶术 丝状角膜病变 病因 

分 类 号：R779.63[医药卫生—眼科]