自体角膜缘干细胞移植与常规翼状胬肉切除术疗效比较  

Comparison of simple excision of pterygium and combined excision of pterygium with stem cell transplantation of limbus cornea

作　　者：黄焱[1] 杨静[1] 张娣[1] 马惠杰[1] 廖凯[1] 沈平[1] 袁安[1] 

机构地区：[1]四川省成都市第二人民医院眼科,610017

出　　处：《眼科新进展》2009年第1期57-58,共2页Recent Advances in Ophthalmology

摘　　要：目的通过翼状胬肉单纯切除术及翼状胬肉切除加自体角膜缘干细胞移植术2种手术方式治疗翼状胬肉,比较其治愈及复发情况及角膜上皮修复时间,评价其疗效。方法将86例(88眼)翼状胬肉患者随机分为翼状胬肉单纯切除术组(A组)43例44眼及翼状胬肉切除加自体角膜缘干细胞移植术组(B组)43例44眼,组间比较采用χ2检验比较其疗效。结果A组10例10眼复发,B组仅有1例1眼复发,2组比较差异有统计学意义(P<0.05);A组角膜上皮修复时间平均为(5.15±0.92)d,B组角膜上皮修复时间平均为(3.36±0.82)d,2组比较差异有统计学意义(P<0.05)。结论翼状胬肉切除加自体角膜缘干细胞移植术可以降低复发率,缩短角膜上皮修复时间,是治疗翼状胬肉较为安全有效的方法。Objective To evaluate the curative effect and compare the curative and recurrent situation between two operative methods, simple excision of pterygium and combined excision of pterygium with stem cell transplantation of limbus cornea, for the treatment of pterygium. Methods Eighty-six cases （88 eyes） with pterygium were randomly divided into 2 groups according to operative method. Curative effect was compared between two groups with chi-square test. Results Ten cases （ 10 eyes） recurred in group A, and 1 case （ 1 eye） in group B. There was statistical significant difference （P 〈 0.05 ）. The average repair time of epithelium was （5.15 ± 0.92 ） d in group A, and （3.36 ± 0.82 ） d in group B. There was significant difference （ P 〈 0.05 ）. Conclusion Excision of pterygium combined with stem cell transplantation of limbus cornea, an effective method to treat pterygium, can reduce the recurrence and lower the repair time of eoithellum.

关 键 词：翼状胬肉 角膜缘干细胞 移植 

分 类 号：R779.6[医药卫生—眼科]