眼前节相干光断层扫描仪与Orbscan Ⅱ及超声法眼前节生物测量对比研究  

ComparatirestudyofanteriorsegmentparametersmeasurementbyOCT,Orbscan,andA-scanultrasound

作　　者：庞辰久[1] 宋晓虹[1] 王丽娅[1] 

机构地区：[1]河南省眼科研究所,河南省眼科中心,郑州450003

出　　处：《中国实用眼科杂志》2009年第1期20-23,共4页Chinese Journal of Practical Ophthalmology

摘　　要：目的比较眼前节相干光断层扫描仪（AS—OCT）与Orbscan Ⅱ以及超声法眼前节生物测量结果，为临床应用提供参考。方法对33例（66只眼）近视眼患者分别行AS—OCT，Orbscan Ⅱ以及A型超声测量仪（DGH550和DGH4000）进行眼前节生物测量，获取角膜中央厚度（CCT），前房深度（ACD），角膜直径，瞳孔直径以及前房角度数，进行对比分析。结果AS—OCT，Orbscan Ⅱ以及超声法测量CCJ、分别为（532．32±35．26）nm，（538．45±38．31）p,m，（555．82±37．63）μm，两两比较各组差异均有统计学意义（P〈0．01）。相关性分析显示三种方法中两两间均呈正相关，相关系数r=0．92、0．91、0．95；ACD分别为（3．19±0．21）mm，（3．08±0．24）mill，和（3．27±0．23）mm，两两间差异也均有统计学意义（P＜0．01）。OCT法测量瞳孔直径为（5．5±0．93）mm，Orbscan法测量结果为（4．5±0．75）mm，二者相差（-1．00±0．68）mm，差异有统计学意义（t=11．95，P=0．000），95％置信区间（0．84，1．17）。OCT测量房角度数均大于Orbscan测量结果，在180度二者相差1．58度，差异无统计学意义（t=1．58，P=O．119），在0度相差2．89度，差异有统计学意义（t=2．89，P=0．005）。结论AS—OCT测量角膜中央厚度较Orbscar Ⅱ 以及超声法测量结果薄，前房深度较Orbsean结果深，更接近于超声测量结果。房角角度测量结果与Orbscan结果近似，且能直观显示房角结构；眼前节OCT快速，非接触，在眼前节生物测量有广泛的应用前景。Objective To compare the accuracy of anterior segment OCT with Orbscan and A ultrasound in measuring anterior segment parameters.Methods Anterior segment parameters in 66 eyes of 33 myopic patients were measured with OCT, Orbscan and A-scan ultrasound.The central corneal thickness （CCT）, anterior chamber depth（ACD ）were acquired by the three methods, corneal diameter（ W to W）, anterior chamber width,pupil diameter, and anterior chamber angle were measured by OCT and Orbscan.Results The CCTs were （532.32± 35.26）p m, （538.45± 38.31）μ m,and （555.82± 37.63）p m,measured by AS-OCT, Orbscan, and A-scan ultrasound.There were significant differences between each of them （P 〈0.01 ）, and also positive correlations were found.The ACD were （3.19± 0.21 ）mm, （ 3.08± 0.24 ）mm, and（ 3.27±0.23 ）mm, re- spectively measured by OCT, Orbcan and ultrasound.There were significant differences between each of them. Pupil diameterwere（5.5± 0.93 ）mm,and（4.5±0.75）mmmeasuredbyOCT and Orbscan.The differencewas（-1.00± 0.68）mm,asignificantdifferencewasfound（t=11.95,P=0.000）,95%CI（0.84,1.17）o Thedifferenceofanteriorchamberanglewere 158° inposition 180° （P=0.119）and 2.89° inposition0° （P〈0.01）measure by OCT and Orbscano Conclusion The CCT was thinner obtained by OCT than by Orbsean and A-scan ultrasound,ACD was deeper than by Orbscan and more close to A-scan ultrasound.The anterior chamber angle were similar in both instruments. AS-OCT provide noncontact,rapid,simple and accurate anterior segment parameters and furthermore a clear anterior segment image.It is a useful instrument in measuring anterior segment parameters.

关 键 词：眼前节 相干光断层扫描仪 ORBSCAN Ⅱ 角膜中央厚度 前房深度 前房角度 

分 类 号：R778.11[医药卫生—眼科] R322.91[医药卫生—临床医学]