羊膜移植联合结膜瓣遮盖术防止角膜穿孔  

Treatment of corneal near-perforation by amniotic membrane transplantation combined with conjunctival flap covering.

作　　者：胡建章[1] 刘瑞英[1] 朱梅红[1] 韩晓丽[1] 朱学军[1] 徐国兴[1] 

机构地区：[1]福建医科大学附属第一医院福建省眼科研究所,福州350005

出　　处：《中国实用眼科杂志》2009年第1期62-64,共3页Chinese Journal of Practical Ophthalmology

基　　金：基金项目：福建省教育厅科研基金（K03023）,福建省卫生厅青年科研基金（2007-2-1）福建省科技厅青年人才项目（2008F3041）

摘　　要：目的 探讨羊膜移植联合结膜瓣遮盖术防止角膜穿孔的临床疗效。方法采用羊膜移植联合结膜瓣遮盖治疗难治性角膜炎致角膜濒临穿孔24例，术后继续局部药物治疗，随访3～10个月，观察角膜愈合情况。结果术后均未见羊膜植片的急性排斥反应，所有手术病例无一出现角膜穿孔，角膜溃疡逐渐修复，角膜基质有不同程度的增厚，多数患者术后视力均有不同程度的提高。结论羊膜移植联合结膜瓣遮盖是治疗角膜濒临穿孔的有效方法。Objective To investigate the clinical effect on treatment of corneal near-perforation by amniotic membrane transplantation combined with conjunctival flap covering.Methods 24 cases of keratitis near-perforation were treated using amniotic membrane transplantation combined with conjunctival flap covering, and continually received local drug treatment after operation.All the patiens were followed up for 3 to 10 months, and the corneal healing was observed.Result No acute rejection was observed after arnniotic mem- brane transplantation in all patients.The infection and inflammation were controlled, corneal ulcer was gradual- ly recovered, and no corneal perforation was found in all eyes after surgery.Postoperative visual acuity of most patients was improved in different degree.Conclusions Amniotic membrane transplantation combined with conjunctival flap covering was an effective method to treat corneal near-perforation.

关 键 词：羊膜移植 结膜瓣遮盖 角膜溃疡 濒临穿孔 

分 类 号：R779.6[医药卫生—眼科] R779.65[医药卫生—临床医学]