DWI对胰腺癌的诊断价值  

Study of the Value of DWI in the Diagnosis of Pancreatic Carcinoma

作　　者：李文娣[1] 袁曙光[1] 闫东[1] 张琳琳[1] 王加艳[1] 普成荣[1] 

机构地区：[1]昆明医学院第二附属医院放射科,昆明650101

出　　处：《放射学实践》2009年第1期59-61,共3页Radiologic Practice

摘　　要：目的:探讨磁共振扩散加权成像(DWI)及表观扩散系数(ADC)对胰腺癌诊断价值。方法:搜集胰腺癌患者35例,正常对照组共32例。DWI选用b值分别为50、400、700 s/mm2,分别测量胰腺癌组织、癌周胰腺组织及正常对照组的ADC值,并进行对比分析;分别测量胰腺癌组织在T2WI,DWI(b=400 s/mm2)及磁共振增强扫描图像中病灶最大直径,并进行分析。结果:3组b值所测得ADC值统计结果示胰腺癌组织与正常对照组、癌周胰腺组织之间均有统计学意义;正常对照组与癌周胰腺组织之间均无统计学意义。胰腺癌组织在T2WI,DWI(b=400s/mm2)及动态增强图像中最大直径测量无统计学差异。结论:DWI可以较清楚地显示胰腺癌病灶,b值为400 s/mm2时图像效果最佳,与ADC值测定共同分析对胰腺癌病灶的检出有价值。Objective：To evaluate the value of diffusion weighted imaging （DWI） and apparent diffusion coefficient （ADC） in the diagnosis of pancreatic carcinoma. Methods： 35 patients with pancreatic carcinoma and 32 normal control subjects were collected. Diffusion weighted magnetic resonance imaging （DWI） was performed, the b value in DWI was： 50s/mm^2 ,400s/mm^2, and 700s/mm^2. The ADC value of the pancreatic carcinoma, the pancreatic tissue adjacent to the tumor and the normal control subject were measured respectively and analyzed. The largest diameter of the pancreatic cancer on T2WI, DWI （b value was 400s/mm^2） ,and dynamic enhanced MRI were measured and analyzed. Results：Of the 3 groups with different b value,the ADC value of pancreatic carcinoma showed significant statistical differences compared with that of the non cancerous tissue and normal control group, but the ADC value of the non-cancerous tissue and normal control group showed no significant difference. No statistical difference was existed in the biggest diameter of pancreatic cancer in T2WI, DWI and dynamic enhanced MRI. Conclusion： The pancreatic carcinoma can be clearly displayed on DWI, the DWI image quality was the best as b value 400s/mm^2. Analysis of DWI in combination with ADC value is helpful in the detection of pancreatic carcinoma foci.

关 键 词：胰腺肿瘤 磁共振成像 扩散加权成像 

分 类 号：R735.9[医药卫生—肿瘤] R455.2[医药卫生—临床医学]