肝硬化并门脉高压性肠病42例  

Clinical analysis of 42 hepatocirrhotic patients with portal hypertensive colonopathy

作　　者：任习芳[1] 姚诘华[1] 郑宗军[1] 龚发良[1] 

机构地区：[1]湖北省宜昌市第一人民医院消化内科,湖北省宜昌市443000

出　　处：《世界华人消化杂志》2008年第36期4115-4117,共3页World Chinese Journal of Digestology

摘　　要：目的:探讨门脉高压性肠病与肝功能分级、门脉高压性胃病、食管静脉曲张的关系.方法:对42例肝硬化患者进行常规结肠镜检查,跟踪随访两年,并对其并发PHC进行分析.结果:42例肝硬化患者中,PHC发生率52%,食管静脉曲张发生率为79%,其中行食管静脉曲张硬化剂及套扎治疗者分别为26%、38%.PHG发生率为55%.随访跟踪两年,发现51%的患者发生下消化道出血.PHC发病率没有随肝功能分级加重(χ2=2.64,P>0.05)、食管静脉曲张程度增加(χ2=1.84,P>0.05),下消化道出血与PHC发病率存在明显相关性(χ2=13.14,P<0.05).结论:肝硬化患者PHC发病率没有随肝功能分级、食管静脉曲张严重程度增加而上升,但PHC是出现下消化道出血的重要因素.AIM： To investigate the clinical characteristics of portal hypertensive colonopathy （PHC） in patients with hepatocirrhosis and to examine its association with liver function, esophageal varices and portal hypertensive gastropathy. METHODS： Forty-two patients with liver cirrhosis underwent colonoscopy and were followedup for 2 years. Incidence rate of portal hypertensive colonopathy was calculated. RESULTS： Incidence rate of PHC was 52%, and for esophageal varices, 79%. Previous sclerotherapy or band ligation treatment for esophageal varices were carried out in 26% and 38% of the patients, respectively. Portal hypertensive gastropathy was observed in 55% of the patients. All of the patients were followed up for at least 2 years, 51% developed lower gastrointestinal bleeding. The incidence rate of PHC was neither increased with increased grade of liver function （χ^2 = 2.64, P 〉 0.05）, nor with esophageal varicosity （χ^2 = 1.84, P 〉 0.05）. However, lower gastrointestinal bleeding was correlated with PHC （χ^2= 13.14, P 〈 0.05）. CONCLUSION： Colonic lesions are frequent in cirrhotic patients, these lesions are not specific for the disease and are not correlated with degree of cirrhosis, with esophageal varices, but correlated with bleeding from the lower gastrointestinal tract.

关 键 词：肝硬化 门脉高压性肠病 肝功能 食管静脉曲张 

分 类 号：R575.2[医药卫生—消化系统]