LEEP治疗宫颈上皮内瘤变924例临床分析  

Clinical analysis of 924 patients with cervical intraepithelial neoplasia treated by loop electrosurgical excision procedure

作　　者：王玲[1] 姚红霞[1] 王海云[1] 吴红[1] 马爱国[1] 

机构地区：[1]上海同济大学附属第一妇婴保健院,200040

出　　处：《中国妇产科临床杂志》2009年第1期34-36,共3页Chinese Journal of Clinical Obstetrics and Gynecology

摘　　要：目的探讨高频电波刀环形电切术(LEEP)在宫颈上皮内瘤变(CIN)诊治中的价值。方法回顾性分析2004年1月～2007年6月我院924例宫颈阴道镜下多点活检和LEEP治疗CIN患者的临床资料,比较阴道镜下多点活检和LEEP术后的病理结果。结果LEEP与阴道镜下多点活检的病理结果符合率为85.50%,其中14.50%(134/924)LEEP术后病理较阴道镜下多点活检程度重,43.83%(405/924)病理程度较阴道镜活检轻。LEEP术后,发现早期浸润癌4例(0.43%);CINⅢ级累腺19例(2.06%)。随诊6～32个月,无一例复发。结论LEEP在治疗CIN中具有诊断和治疗的价值。Objective To evaluate cervical conization by loop electrosurgical excision procedure （LEEP） in diagnosis and management of cervical intraepithelial neoplasia （CIN）. Method From January 2004 to June 2007, 924 CIN patients underwent multiple biopsies under colposcope and LEEP at Shanghai First Maternity and Infant Health Care Hospital, whose pathological diagnosis was retrospectively compared and prognosis was analyzed. Results The consistency rate in pathological diagnosis of biopsy and LEEP was 85.50% （790/924）. The pathological diagnosis was more severe than multiple biopsies under colposcope in 14. 50% （134/924）; and less severe in 43. 83% （405/924）. Four cases （0. 43%） of invasive cancer and 19 （2.06%） of CINⅢ involved the gland were diag- nosed after LEEP. They are followed up for 6 to 32 months and no recurrence was found. Conclusions Cervical loop electrosurgieal excision procedure （LEEP） conization plays a very important role in diagnosis and treatment of CIN.

关 键 词：宫颈上皮内瘤变 高频电波刀环形电切术 阴道镜 

分 类 号：R737.33[医药卫生—肿瘤]