经电子支气管镜介导微波联合全身化疗治疗晚期肺癌的临床研究  

Clinical research of fiberoptic bronchoscopy guided microwave coagulation treatment and chemotherapy of advanced lung cancer

作　　者：李秀忠[1] 张锦[1] 陈娟[1] 崔丽萍[1] 

机构地区：[1]宁夏医科大学附属医院,宁夏银川750004

出　　处：《宁夏医学杂志》2009年第1期44-45,共2页Ningxia Medical Journal

基　　金：宁夏卫生厅医疗卫生科研项目(WZ00513)

摘　　要：目的探讨应用电子支气管镜(气管镜)介导微波联合全身化疗治疗晚期肺癌的疗效。方法将60例晚期中央型肺癌患者分为治疗组和对照组;治疗组30例采用气管镜介入微波联合全身化疗,对照组30例只进行全身化疗。结果治疗组30例中微波治疗平均3.3次,症状改善率90%,气管镜下病灶好转率76.7%,KPS评分提高者93.3%,胸部CT及X线示肺不张或阻塞性肺炎好转率66.7%,与对照组相比差异有统计学意义(P<0.01)。结论经电子支气管镜介导微波联合全身化疗治疗晚期肺癌可显著改善患者的临床症状,此联合方法优于单纯化疗。Objective To study the effect of fiberoptic bronehoseopy guided microwave coagulation treatment and chemotherapy in the treatment of patients with advanced lung cancer. Methods 60 cases with advanced lung cancer were randomized assigned to two groups （n =30）. Study group received fiberoptic bronehoscopy guided microwave coagulation treatment and chemotherapy, and control group received chemotherapy only. Results The total response rate was 90%. And the rate of lesions improvement under bronehoseopy was 76.7% ; the rate of KPS improvement was 93.9% ; lesions improvement under CT was 66.7%, there was significant statistic differ- ence between the two groups （ P 〈 0.01 ）. Conclusion Fiberoptic bronchoscopy guided microwave coagulation treatment combined chemotherapy can enhance the efficacy of chemotherapy.

关 键 词：肺癌 支气管镜 微波 

分 类 号：R734.2[医药卫生—肿瘤]