左卡尼汀强化TPN对老年结直肠癌患者术后的影响  

Effect of levocarnitne-enriched TPN on old patients with colorectal cancer after surgery

作　　者：孙浩[1] 周明川[1] 

机构地区：[1]重庆市第三人民医院普外科,重庆400014

出　　处：《四川医学》2009年第1期61-63,共3页Sichuan Medical Journal

摘　　要：目的探讨L-CN强化的全胃肠外营养(TPN)对老年结直肠癌患者根治术后的作用。方法36例手术和病理学确诊的老年结直肠癌患者,随机分成标准TPN对照组(TPN组)和L-CN强化组(L-CN组),分别检测术前和术后血Alb、PAB、TG、CRP、ALT、Glu水平,评估术后体力状况的分级并观察胃肠道功能恢复时间。结果L-CN组术后第6天Alb、PAB、TG、CRP恢复至正常水平或维持术前水平,与TPN组相比P<0.05;肝功能一过性损害的发生率,血糖一过性升高的发生率,两组间比较P<0.01;L-CN组患者肠功能恢复时间明显短于TPN组,差异具有统计学意义(P<0.05);两组体力状况分级差异虽无统计学意义,但L-CN组患者的恢复要好于TPN组。结论L-CN强化的TPN是老年结直肠癌患者术后营养支持治疗的合适选择。Objective To discuss the effect of levocarnitine-enriched TPN on patients with colorectal cancer after radical corrections. Methods Thirty-six patients who were diagnosed as colorectal cancer by operation and pathology were randomly divided into TPN group and L-CN-enriched group.Alb,PAB、TG,CRP, ALT and Glu level was detected respectively in both groups before and after operation,classification of physical status after operation was evaluated and recovery time of gastrointestinal tract function was observed. Results AIb,PAB,TG and CRP on the 6th day after operation in L-CN group recovered to or maintained the preoperative level compared with TPN group（ P 〈 0.05） ;Transient damage incidence of liver function was compared between bout groups,the incidence of transient-hyperglycemia was compared between both groups（ P 〈 0.01） ; Recovery time of intestinal function was remarkably shorter in L, CN group than that in TPN group,and the difference was significant（ P 〈 0.05） ; There was no significant difference in the physical status daasification between both groups,but patients in L-CN group recovered better than those in TPN group. Conclusion Levocamitine-en- riched TPN is a suitable choice for the nutritional support treatment for patients with calorectal cancer after surgery.

关 键 词：左卡尼汀 全胃肠外营养 术后 

分 类 号：R735.3[医药卫生—肿瘤]