脑梗塞患者白细胞变形能力和粘附功能的动态变化  

The Diurnal Variations of Leukocyte Deformability and Leukocyte Adhesion Function in Patients with Cerebral Infarction

作　　者：李玫[1] 瞿浩[1] 

机构地区：[1]贵州省人民医院神经内科

出　　处：《贵阳医学院学报》1998年第2期160-162,共3页Journal of Guiyang Medical College

摘　　要：采用红细胞变形能力测定仪和血栓血小板粘附两用仪，检测４２例健康人和４８例脑梗塞患者白细胞滤过指数（ＩＦ）和白细胞粘附率（ＬＡＲ）早晚动态变化，探讨白细胞变形能力（ＬＤ）和白细胞粘附功能（ＬＡＦ）与脑梗塞发病之间的关系。结果两组中，ＩＦ和ＬＡＲ早晨较下午高（Ｐ＜００５，Ｐ＜００１）；脑梗塞患者ＩＦ和ＬＡＲ较对照组明显增高（Ｐ＜００１）。The diurnal Variations of leukocyte deformability(LD) and leukocyte adhesion function (LAF) were measured in patients with cerebral infarction to study the correlation of the attacks of cerebral infarction with LD and LAF.Using erythrocyte deformability apparatus,thrombus and platelet adneslon dual purpose apparatus were used to measure the diurnal variation of leukocyte filtration index(IF) and ledkocyte adhesion rat (LAR) in 42 healthy people and 48 patients with cerebral infarction.The leukocyte IF and LAR in patients and controls were significantly higher in the morning than in the afternoon (P<0 05,P<0 01).The leukocyte IF and LAR were significantly higher in patients with cerebral infarction than those in controls(P<0 01). Thess results indicate that the phenomenon of the frequent occurrence of attacks of cerebral infarction in the morning might be related to the diurnal variation of LD and LAF.

关 键 词：脑梗塞 白细胞 血液流变学 变形能力 粘附功能 

分 类 号：R743.33[医药卫生—神经病学与精神病学]