原发性卵巢小细胞癌（高钙血症型）一例临床病理分析并文献复习  

Clinicopathological Study on Primary Ovarian Small Cell Carcinoma （hypercalcemic-type）

作　　者：汪娟[1] 

机构地区：[1]江苏省江阴市人民医院病理科,江苏江阴214400

出　　处：《医学临床研究》2009年第1期90-92,共3页Journal of Clinical Research

摘　　要：【目的】探讨原发性卵巢小细胞癌（高钙血症型）（OSCCHT）的临床病理特征，并对其诊断和鉴别诊断进行讨论。【方法】报告1例卵巢OSCCHT并结合文献对其临床病理特征进行分析。【结果】原发性卵巢小细胞癌是卵巢的一种起源不明确的少见的高度恶性小细胞肿瘤，其病理组织学分型包括高钙血症型和肺型，0SCCHT2／3患者伴血钙升高，肿瘤摘除后血钙恢复正常，组织学特点主要由大小较一致的小细胞组成，可见散在分布的滤泡样结构，40％肿瘤内出现大细胞。【结论】本病预后差，联合治疗（特别是放疗）可能延长生存时间。[Objective] To study the ctinicopathological features of primary ovarian small cell carcinoma （hypercalcemic-type） （OSCCHT） and to discuss its diagnosis and differential diagnosis. [Methods]The clinical and histological characteristics in a case of ovarian OSCCHT was analyzed by immunohistochemical meth- od. And this disease was reviewed. [Results] OSCCHT was an extremely rare tumor with a high grade of malignancy, and its origination was unknown. It was classified into hypercalcemic type and pulmonary type by histology and pathology. Two third of the patients with OSCCHT were concomitant with hypercalcinemia, and their blood calcium was normal after tumor excision. The clinicopathological features of OSCCHT were the composition of equirotal small cells and sporadic follicular configuration. Forty percent of tumors had big cells. [Conclusion] The prognosis of OSCCHT is poor. The combined therapy （especially radiation therapy） might make the survival time longer.

关 键 词：癌 小细胞/病理学 卵巢肿瘤/病理学 

分 类 号：R737.31[医药卫生—肿瘤]