急性胰腺炎几项实验诊断指标的比较  

Comparison of several laboratory diagnostic parameters of acute pancreatitis

作　　者：刘连庚 

机构地区：[1]江苏省盐城市中医院检验科,224002

出　　处：《检验医学与临床》2009年第3期172-173,共2页Laboratory Medicine and Clinic

摘　　要：目的为了探讨血、尿淀粉酶,淀粉酶清除率与肌酐清除率比值(ACCR)以及尿胰蛋白酶原-2(Tpg-2)测定对急性胰腺炎(AP)的临床诊断价值。方法对67例急性胰腺炎患者,42例非胰腺炎急腹症患者和60例健康体检人员进行血、尿淀粉酶,血、尿肌酐及尿胰蛋白酶原-2测定。结果急性胰腺炎尿胰蛋白酶原-2诊断特异度和敏感度最高,分别为95.2%、95.5%,其次是淀粉酶清除率与肌酐清除率比值,其特异度和敏感度分别为85.7%、92.5%,血淀粉酶(Samy)特异度和敏感度分别为78.6%、80.6%,尿淀粉酶(Uamy)特异度和敏感度分别为69.0%、73.1%。结论尿胰蛋白酶原-2和淀粉酶清除率与肌酐清除率比值是目前诊断急性胰腺炎较好的早期指标,优于血尿淀粉酶。Objective To discuss the clinical value of the determinations of serum amylase （Samy）, urinary amylase （Uamy） ,amylase creatinine clearance ratio （ACCR） and urinary trypsinogen-2 （Tpg-2） in diagnosis of acute pancreatitis （AP）. Methods Samy, Uamy, serum creatinine, urine creatinine and Tpg 2 were tested in 67 patients with AP,42 acute abdomen patients without AP and 60 health controls; and then ACCR was calculated. Results Tpg-2 was found with the highest specificity （95. 2%） and sensitivity （95. 5）, followed by ACCR （85. 7% and 92.5 %, respectively）, Samy （78.6 % and 80. 6 %, respectively） and Uamy （69.0 % and 73.1%, respectively）. Conclusion Tpg-2 and ACCR are confirmed as ideal markers in early diagnosis of acute pancreatitis,superior to Samy and Uamy.

关 键 词：急性胰腺炎 淀粉酶清除率 肌酐清除率 尿胰蛋白酶原-2 

分 类 号：R576[医药卫生—消化系统]