艾滋病合并消耗综合征的营养治疗疗效观察  

Supplementary nutrition therapy for washing syndrome in patients with AIDS

作　　者：翁田波[1] 魏霞[1] 蔡卫平[2] 陈谐捷[2] 王建[2] 洪文昕[2] 

机构地区：[1]广州市第八人民医院营养科,510060 [2]广州市第八人民医院感染科,510060

出　　处：《实用医学杂志》2009年第3期413-414,共2页The Journal of Practical Medicine

摘　　要：目的:探讨营养辅助治疗艾滋病合并消耗综合征的疗效。方法:应用回顾性分析方法研究艾滋病合并消耗综合征患者40例,分成A、B两组。两组均采用了HAART治疗,三正餐为半流饮食。A组在两餐之间增加营养均衡的营养素,共加餐3次/d,840kJ/次(200kcal/次)。A组全日提供热量为6300kJ(1500kcal)。B组全日提供的热量是3780kJ(900kcal)。结果:治疗1个月后,A组体重平均增加(3.8±7.2)kg;B组增加(1.36±5.7)kg。A组BMI值平均增加(1.75±2.79);B组增加(0.40±3.14)。A组CD4细胞计数平均增加(21.50±30.56)个/uL;B组增加(12.75±16.75)个/μL。A组与B组比较差异有统计学意义。结论:营养辅助治疗艾滋病合并消耗综合征患者可显著改善机体营养状态。有助于患者免疫功能重建。Objective To explore the efficacy of supplementary nutrition for wasting syndrome in patients with AIDS. Methods The data of nutrition intake in 40 AIDS patients with wasting syndrome who had been on highly active antiretroviral therapy （HAART） were retrospectively analyzed. All patients had semi-liquid diet for three meals and were assigned to receive additional well-balanced nutrients thrice between lunch and dinner with a daily intake of 6 300 kJ （group A） or no additional nutrients with only 3 780 kJ per day （group B）. Results One month following nutrition therapy, there were significant differences between group A and group B in average weight gain, BMI increase, and elevation of CD4 cell count [（3.8 ± 7.2）kg vs. （1.36 ± 5.7） kg, 1.75 ± 2.79 vs. 0.40 ± 3.14, and （21.50 ± 30.56）/uL vs. （ 12.75 ± 16.75）/uL; P 〈 0.05]. Conclusions Supplementary nutrition therapy may markedly improve the nutritional state in AIDS patients with wasting syndrome, which is beneficial for restoring the immune function.

关 键 词：获得性免疫缺陷综合征 消耗综合征 营养素 

分 类 号：R512.91[医药卫生—内科学] R587.1[医药卫生—临床医学]