骨髓外局部组织检出海蓝组织细胞的研究  

Study on Sea Blue Histocytes Detected outside Bone Marrow

作　　者：李继广[1] 王克强[2] 

机构地区：[1]聊城市第二人民医院,山东聊城252600 [2]山东省泰山医学院附属医院,山东泰安271000

出　　处：《现代检验医学杂志》2009年第1期106-107,共2页Journal of Modern Laboratory Medicine

摘　　要：目的前瞻性研究骨髓外组织检出海蓝组织细胞的特点及意义。方法对临床上所有进行穿刺及脱落细胞学检查的标本同时做H—E染色和瑞氏-姬姆萨染色，然后镜检查找海蓝组织细胞。对被检出海蓝组织细胞的患者再行骨髓穿刺检查，确认骨髓中是否也有海蓝组织细胞。临床上重点观察其有无肝、脾大，皮肤有无出血斑，BPC是否减少。结果从5760例被检标本中检出海蓝组织细胞8例，此8例患者骨髓中未见海蓝组织细胞，临床上无肝、脾肿大，皮肤无出血斑，BPC无减少。结论骨髓外检出海蓝组织细胞的患者临床表现与“海蓝组织细胞增生症”不同，可能为骨髓外局部组织海蓝组织细胞增生的缘故，认为骨髓外组织也可分化产生海蓝组织细胞。Objective Prospective study on the characteristics and significance of sea blue histocytes detected outside bone marrow. Methods All specimens from aspiration cytology and detached cytology studies were examed for sea blue histocytes after stained by hematoxylin-eosin （H-E） and Wright-Giemsa. For those with sea blue histocytes found outside BM, BM aspirations were performed to determine whether or not such cells were also in BM. Clinical observations focused on the presence of hepatomegaly,splenomegaly,petechia and thrombocytopenia. Results Of the 5 760 cases examined, sea blue histocytes outside BM were detected in 8,who had neither sea blue histocytes in BM nor hepatomegaly,splenomegaly or thrombocytopenia. Conclusion The clinical features of the patients with sea blue histocytes detected outside BM were different from those of ＂sea blue histocytosis＂. These cells were probably originated from proliferation of sea blue histocytes in local tissue other than BM. It is considered that extra-marrow tissues may also differentiate to produce sea blue histocytes.

关 键 词：海蓝组织细胞 海蓝组织细胞增生症 骨髓外组织 骨髓 

分 类 号：R446.8[医药卫生—诊断学]