空肠弯曲菌感染与Guillain-Barré综合征  

Campylobacter jejuni infection and Guillain Barré Syndrome

作　　者：许庆成[1] 侯熙德[1] 金庆文[1] 姚娟[1] 储旭华[1] 王宁山[1] 

机构地区：[1]南京医科大学附属南京第一医院神经内科

出　　处：《中华神经科杂志》1998年第2期72-73,共2页Chinese Journal of Neurology

基　　金：江苏省教委基金

摘　　要：目的研究空肠弯曲菌感染与ＧｕｉｌａｉｎＢａｒé综合征发病的关系。方法用ＥＬＩＳＡ方法检测４０例ＧｕｉｌａｉｎＢａｒé综合征病人的血清和脑脊液中的空肠弯曲菌ＩｇＧ、ＩｇＭ、ＩｇＡ等抗体，并和其他神经系统疾病组以及正常对照组各２０例进行比较。结果ＧｕｉｌａｉｎＢａｒｒé综合征病人组空肠弯曲菌感染率（５０％）高于两个对照组（均为３０％），但差异无显著意义。结论空肠弯曲菌感染是否是ＧｕｉｌａｉｎＢａｒé综合征的重要发病诱因尚有待商榷。Objective To study the relationship between campylobacter jejuni (CJ) infection and Guillain barré syndrome (GBS). Methods The method of ELISA was used to detect the antibodies (IgG、IgM、IgA) to CJ in the serum and cerebrospinal fluid (CSF) of the 40 patients with GBS. The control groups consisted of the patients with other neurologic diseases and normal people.Result The recent infection rate of CJ in GBS group was higher (50%) than that (30%) of the controls, but not statistically significant Conclusion The real relationship between GBS and CJ is still uncentain.

关 键 词：空肠弯曲菌 G-B综合征 发病 

分 类 号：R745.430.2[医药卫生—神经病学与精神病学]