槟榔果实的酚类化学成分与抗菌活性的初步研究  

Phenolic Constituents from the Fruits of Areca catechu and Their Anti-bacterial Activities

作　　者：张兴[1] 梅文莉[1] 曾艳波[1] 刘建[1] 戴文君[1] 戴好富[1] 

机构地区：[1]中国热带农业科学院热带生物技术研究所,海口571101

出　　处：《热带亚热带植物学报》2009年第1期74-76,共3页Journal of Tropical and Subtropical Botany

基　　金：973计划前期研究专项(2007CB116306);国家科技支撑计划(2007BA127B04)

摘　　要：从槟榔(Areca catechu L.)果实乙醇提取物的乙酸乙酯萃取部分分离得到了5个酚类成分,经波谱分析,分别鉴定为:异鼠李素(1)、金圣草黄素(2)、木犀草素(3)、(±)-4',5-二羟基-3',5',7-三甲氧基黄烷酮((4a,4b)和巴西红厚壳素(5)。以上化合物均为首次从该属植物中分离得到。用滤纸片琼脂扩散法表明化合物(5)对MRSA和金黄色葡萄球菌有明显抑制作用。Five phenolic compounds were isolated from ethanol extraction of fruits ofAreca cateehu. On the basis of spectroscopic evidence （NMR, MS, etc） and spectral data, they were identified as isorhamnetin （1）, chrysoeriol （2）, luteolin （3）, （±）-4＇,5-dihydroxy-3＇,5＇,7-trimethoxyflavonone （4）, and jacareubin （5）. All the compounds were isolated from Areca for the first time. Anti-bacterial activities showed that compound 5 had significant inhitory effect on methicillin-resistant Staphylococcus aureus （MRSA） and Staphylococcus aureus.

关 键 词：槟榔 酚类成分 抗菌活性 

分 类 号：R284[医药卫生—中药学] R285[医药卫生—中医学]