原发性闭角型青光眼临床前期眼与窄房角正常眼的解剖结构比较  被引量:10

Comparison of anatomic structure between preclinical phase of PACG and normal eyes with narrow angles

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作  者:冯朝晖[1] 周爱意[1] 王肖华[1] 孙乃学[1] 

机构地区:[1]西安交通大学医学院第二附属医院眼科,陕西省西安市710004

出  处:《眼科新进展》2009年第2期118-120,共3页Recent Advances in Ophthalmology

基  金:陕西省科技攻关计划基金资助[编号:2005K12-G5(3)]~~

摘  要:目的比较急性原发性闭角型青光眼(primary angle closure glaucoma,PACG)临床前期眼和窄房角正常眼的眼部解剖结构差异。方法应用B超结合自行开发的计算机图像处理软件以及超声生物显微镜测量,计算PACG临床前期眼36例36眼和窄房角正常眼20例40眼的眼部解剖参数并进行比较。结果急性PACG临床前期组的晶状体中央部厚度为(4.79±0.47)mm,大于窄房角正常组(4.45±0.32)mm(P<0.01);晶状体周边部厚度为(3.41±0.38)mm,大于窄房角正常组(3.21±0.27)mm(P<0.05);虹膜晶状体接触距离为(566.56±116.99)μm,大于窄房角正常组(497.23±109.68)μm(P<0.05),晶状体前表面曲率半径为(7.88±1.30)mm,小于窄房角正常组(10.33±2.52)mm(P<0.01);前房深度为(1839.89±171.40)μm,小于窄房角正常组(2237.45±284.45)μm(P<0.01);房角开放距离为(95.02±36.63)μm,小于窄房角正常组(236.25±82.73)μm(P<0.01);小梁睫状突距离为(724.15±176.10)μm,小于窄房角正常组(856.80±203.97)μm(P<0.01);小梁虹膜夹角(11.59°±4.45°),小于窄房角正常组(24.28°±7.66°)(P<0.01);虹膜晶状体夹角(18.12°±2.38°),小于窄房角正常组(20.01°±3.55°)(P<0.01);眼轴长度为(20.84±0.80)mm,小于窄房角正常组(21.91±1.09)mm(P<0.01);相对晶状体位置(0.2015±0.0112)较窄房角正常组(0.2157±0.0072)靠前(P<0.01)。结论PACG临床前期眼的眼部解剖结构明显不同于窄房角正常眼,其中以房角参数差异最显著。可以考虑将以上参数作为急性PACG早期诊断的参考指标,进一步进行临床观察与研究。Objective To compare the differences of anatomic structure between preclinical phase of acute primary angle closure glaucoma (PACG) and normal eyes with narrow angles. Methods B ultrasound combined with self-developed image processing software and ultrasound biomicroscopy (LrBM) were used to get the anatomical parameters of 35 cases (35 eyes) at preclinical phase and 20 cases (40 eyes) ,and the data had been analyzed by statistical software package. Results Mean central lens thickness at preclinical phase of acute PACG group ( 4.79 ± 0.47 ) mm was thicker than that of normal control (4.45 ± 0.32 ) mm ( P 〈 0.01 ), peripheral lens thickness ( 3.41 ± 0. 38)mm was thicker than normal control (3.21 ±0.27)mm(P 〈0. 05) ,iris-lens contact distance(555.55 ± 116.99 ) μm was larger, than normal control (497.23 ± 109.68 )μm(P 〈 0. 05 ), radius of curvature of anterior lens surface (7. 88 ± 1. 30) mm was smaller than normal control ( 10. 33 ± 2. 52 ) mm ( P 〈 0. 01 ), anterior chamber depth ( 1 839. 89 ± 171.40 ) μm was shallower than normal control (2 237.45 _± 284.45 ) μm(P 〈 0. 01 ),angle opening distance (95. 02 ± 36. 63 ) μm was smaller than normal control (235. 25 ±82.73)ixm(P 〈0. 01 ) ,trabecular ciliary processes distance (724.15 ± 175. 10) μm was shorter than normal control ( 856.80 ± 203.97 ) μm ( P 〈 0. 01 ), trabecular iris angle( 11. 59° ±4.45° ) was narrower than normal control(24.28° ± 7.55°) (P 〈0. O1 ), iris lens angle ( 18.12°± 2.38 °) was smaller than normal control ( 20. 01 ± 3.55 ° ) (P 〈0. 01 ), axial length( 20.84 ± 0. 80 ) nun was shorter than normal control ( 21.91 ± 1.09 ) mm(P 〈 0.01 ), relative lens position(0. 201 5 ± 0. 011 2) was more anterior than normal control (0.215 7 ± 0. 007 2 ) (P 〈0. 01 ), and these differences were statistically significant, Conclusion Anatomic structures of anterior

关 键 词:原发性闭角型青光眼 临床前期 眼部解剖参数 超声生物显微镜 B型超声 

分 类 号:R775.1[医药卫生—眼科]

 

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