糖耐量异常与血管病变及糖基化终产物  

Impaired glucose tolerance,angiopathy and advanced glycation end products

作　　者：詹雅诗[1] 冯烈[1] 

机构地区：[1]暨南大学附属第一医院内分泌科,广东广州510630

出　　处：《中国病理生理杂志》2009年第2期405-408,共4页Chinese Journal of Pathophysiology

摘　　要：The definition of impaired glucose tolerance (IGT) was first introduced by the National Diabetes Data Group at 1979. Recently the morbidity rate of IGT is soaring. About 10%-15% of patients with IGT will progress to type 2 diabetes mellitus (T2DM) which is approximately more than 100 times comparing with normal glucose tolerance people. Angiopathy can be detected in 40% patients with newly diagnosed IGT. Advanced glycation end products (AGEs) are closely related to angiopathy. Meanwhile there is some connection between IGT and AGEs. In this review, the relationship between IGT, agiopathy and AGEs is discussed.The definition of impaired glucose tolerance （IGT） was first introduced by the National Diabetes Data Group at 1979. Recently the morbidity rate of IGT is soaring. About 10% - 15% of patients with IGT will progress to type 2 diabetes mellitus （T2DM） which is approximately more than 100 times comparing with normal glucose tolerance people. Angiopathy can be detected in 40% patients with newly diagnosed IGT. Advanced glycation end products （AGEs） are closely related to angiopathy. Meanwhile there is some connection between IGT and AGEs. In this review, the relationship between IGT, agiopathy and AGEs is discussed.

关 键 词：糖耐量异常 血管病变 糖基化终产物 高级 糖尿病 

分 类 号：R363[医药卫生—病理学]