腹水中CD3、CD8 T淋巴细胞在卵巢癌及盆腹腔结核鉴别诊断中的意义  

The Differential-diagnosis Effect of the Test of CD3,CD8 T lymphocytes in Ascites of Patients with Abdominal Tuberculosis or Ovarian Cancer

作　　者：郭琛[1] 马晓艳[1] 王倩[1] 廖琪[1] 

机构地区：[1]吉林大学第二医院妇产科,吉林长春130041

出　　处：《中国实验诊断学》2009年第2期227-229,共3页Chinese Journal of Laboratory Diagnosis

基　　金：吉林省科技厅资助(20030538-4)

摘　　要：目的探讨腹水中CD3、CD8 T淋巴细胞的检测在卵巢癌及盆腹腔结核鉴别诊断中的价值。方法卵巢癌患者34例,盆腹腔结核患者16例,流式细胞术检测其腹水中CD3、CD8 T淋巴细胞。结果卵巢癌腹水中CD3 T淋巴细胞数量(64.8±5.0%)小于盆腹腔结核腹水中CD3 T淋巴细胞数量(85.7±5.3%)(P<0.01),卵巢癌腹水中CD8 T淋巴细胞数量(30.5±4.7%)大于盆腹腔结核腹水中CD8 T淋巴细胞数量(20.6±3.3%)(P<0.01)。结论腹水中CD3、CD8 T淋巴细胞检测可用作卵巢癌及盆腹腔结核鉴别诊断。Objective This study aimed at through the test of CD3, CD8 T lymphoeytes in ascites to gained the differential diagnosis between the patients with ovarian cancer and the patients with abdominaltuberculosis. Methods 34 cases of epithelial ovarian cancer and 16 casesof abdominal tuberculosis which diagnosed by pathological.Age compared between both with no statistically difference. FCM test the CD3 and CD8 T lymphocytes. The percentage of positive cells expossed the results. Results The amount of CD3 T lymphocytes in ascites of patients with ovarian cancer（64.8 ± 5.0% ）less than CD3 T lymphocytos in ascites of patients with abdominal tuberculosis（85.7 ±5.3 % ）（ P 〈 0.01）, and the amount of CD8 T lymphocytes in ascitos of patients with ovarian cancer（30.5 ± 4.7% ）more than CD8 T lymphocytes in ascites of patients with abdominal tuberculosis（20.6 ± 3.3% ）（ P 〈 0.01）. Conclusion CD3, CD8 T lymphocyte in ascites can be the indicator of differential diagnosis between ovarian cancer and abdominal tuberculosis.

关 键 词：卵巢癌 盆腹腔结核 T淋巴细胞 腹水 鉴别诊断 

分 类 号：R737.31[医药卫生—肿瘤]