赤霉酸分子印迹聚合物及印迹膜的制备与性能研究  

Preparation and recognition properties of GA_3-imprinted polymers/membranes

作　　者：汪国松[1] 杨雪琼[1] 方云山[1] 朱秀芳[1] 张洪彬[1] 丁中涛[1] 

机构地区：[1]云南大学化学科学与工程学院,教育部自然资源药物化学重点实验室,云南昆明650091

出　　处：《化学研究与应用》2009年第2期141-145,共5页Chemical Research and Application

基　　金：国家自然科学基金(30260014)资助;云南省自然科学基金(2006B002Q)资助

摘　　要：以赤霉酸(GA3)为印迹分子,改变功能单体与致孔剂种类合成了四个分子印迹聚合物(MIP1-4)及两个分子印迹膜(MIM1-2)。采用紫外光度法分别测定了印迹分子分别与功能单体丙烯酰胺(AM)和甲基丙烯酸(MAA)间的结合常数和化学计量比(n=2)。平衡结合实验研究表明,以AM为单体制备的MIP1对印迹分子GA3具有更高的结合量和良好的印迹效率。膜渗透及膜过滤实验表明,以AM为单体制备的MIM1对GA3分子具有一定的选择性分离性能。Four gibberellie acid（ GA3 ） -imprinted polymers （ MIP1-4 ） and two GA3 -imprinted membranes （ MIM1-2 ） had been prepared in chloroform or in methanol using different functional monomers（ MAA or AM）, respectively. The interaction between template and functional monomers was studied by UV spectrophotometry,which showed a formation of GA3-monomer complexes with 1：2. The polymeric particles were tested in the equilibrium binding experiment to analyze its adsorption ability to GA3. The recognition properties of MIP and MIM were compared with and prior to those of the NIP and NIM. The permeation experiment showed that MIMl prepared in chloroform using AM as functional monomer, exhibited higher permeation selectivity to gibberellic acid.

关 键 词：分子印迹技术 分子识别 聚合物(膜) 赤霉酸 

分 类 号：O632.51[理学—高分子化学]