肌钙蛋白Ⅰ及乳酸联合监测在肝移植中的意义  

The Significance of Combined Monitoring of cTnI and Lac in Liver Transplanted Patients

作　　者：贾瑛[1] 梁娜[1] 

机构地区：[1]天津第一中心医院,天津300192

出　　处：《透析与人工器官》2008年第4期14-16,共3页Chinese Journal of Dialysis and Artificial Organs

摘　　要：目的探讨肌钙蛋白I(cTnI)及乳酸(Lac)在肝移植患者中的动态变化。方法回顾性分析了56例接受肝移植手术的病例,分为肝硬化组与肝癌组。动态监测术前和术后4个时间点cTnI与Lac的变化。结果两组病人术前Lac值差异无统计学意义(P>0.05),肝硬化组cT-nI高于肝癌组(P<0.01)。术毕至术后3dcTnI及Lac结果肝硬化组均高于肝癌组,且两组病人术后各阶段cTnI及Lac结果均高于术前,差异有统计学意义(P<0.01)。4个时间点cTnI与Lac之间呈正相关(P<0.01)。结论cTnI及Lac的联合监测对肝移植心肌损伤的防治有重要意义。Objective To investigate the dynamic changes of eTnI and Lac in liver transplanted patients. Methods A retrospective analysis of 56 patients who underwent liver transplantation were made. They were divided into two groups： hepatoeirrhosis group 35 cases and liver cancer group 21 cases. And they were eontinuly monitored cTnI and Lac results at four different time periods. Results There was no statisical significance in Lac results be- tween two groups before operation （ P 〉 0. 05 ） , and the eTnI results of hepatocirrhosis group were higher than those of liver cancer group （P 〈 0. 01 ）. There days post operation, hepatocirrhosis group had a higher level of cTnI and Lae results than those of liver cancer group （ P 〈 0. 01 ）. cTnI and Lae results of two groups had a higher level at postoper- ation than preoperation （ P 〈 0. 01 ）. cTnI and Lae show a positive correlation at four different time periods （ P 〈 0. 01 ）. Conclusion The combined monitoring of cTnI and Lac plays an important role in liver transplanted patients who underwent cardiac muscle injury.

关 键 词：肝移植 心肌损伤 肌钙蛋白Ⅰ 乳酸 

分 类 号：R657.3[医药卫生—外科学] R542.22[医药卫生—临床医学]