胃肠道间质瘤92例  

Gastrointestinal Stromal Tumor 92 Cases

作　　者：赵文军[1] 王青[2] 张锐利[1] 林祖朝[1] 邱振明[1] 卢永明[1] 王敏[1] 

机构地区：[1]浙江省温州医学院附属台州医院普外科,临海317000 [2]浙江省温州医学院附属台州医院组织库,临海317000

出　　处：《中国中西医结合外科杂志》2009年第1期22-24,共3页Chinese Journal of Surgery of Integrated Traditional and Western Medicine

摘　　要：目的:探讨胃肠道间质瘤的特点及诊疗方法。方法:对92例患者分别行胃镜下肿瘤局部切除、胃大部分切除、胃楔形切除、腹腔镜下胃楔形切除、胰十二指肠切除、肠段切除、腹会阴联合切除及肿块局部切除等手术,其中4例术后服用甲磺酸伊马替尼巩固治疗。结果:术中及围手术期无死亡,住院时间2～32d,平均11.6d。5例于术后21～73个月死亡,平均52.4个月。结论:缺乏特征性临床表现,目前治疗仍以手术切除为主,术中应行肿瘤局部切除或消化道部分切除。Taizhou Hospital of Zhefiang Province, Linhai （ 317000 ） , China Objective To study the characteristics and diagnosis and treatment of gastrointestinal stromal tumors （GIST）. Methods Ninety - two patients with GIST were treated with gastroscopic local excision, partial gastrectomy, stomach wedge shaped resection, laparoscopic wedge - shaped gastrectomy, pancreatectomy and duodenectomy, bowel resection, Mile＇ s operation and other local mass resection correspondingly. Four of them took imatinib mesylate after opera- tion. Results There was no death in the perioperative stage, the hospitalization time was 2 - 32 d, averaging 11.6 d. Five patients died in 21 to 73 months after operation, with an average period of 52.4 months. Forty- three patients recovered well restoring basic living conditions. Conclusion The diagnosis of GIST is difficult in the preoperative period because of the lack of clinical features. Final diagnosis should be based on pathology and immunohistochemical tests. Positive results of CD117 and CD34 are the most valuable indices. The main choice of treatment is operation.

关 键 词：胃肠道间质瘤 间叶性肿瘤 外科手术 

分 类 号：R730.262[医药卫生—肿瘤]