大鼠大脑中动脉脑缺血模型的影响因素  

Factors Affecting Cerebral Ischemia Model of Rat Established by Middle Cerebral Artery Occlusion(review)

作　　者：江晓峰[1,2] 何玥[3] 胡雪艳[2,4] 张通[2,4] 

机构地区：[1]首都医科大学公共卫生与家庭医学学院,北京市100069 [2]首都医科大学康复医学院,北京市100068 [3]首都医科大学基础医学院,北京市100069 [4]中国康复研究中心北京博爱医院神经康复科,北京市100068

出　　处：《中国康复理论与实践》2009年第2期149-151,共3页Chinese Journal of Rehabilitation Theory and Practice

基　　金：北京市属市管高校人才强教项目-中青年骨干教师计划

摘　　要：影响大鼠大脑中动脉闭塞脑缺血动物模型建立的因素有:大鼠品种、麻醉剂、手术部位和线栓等,其中线栓的选择是模型制作成功的关键,包括线栓的种类、长度、直径、硬度、放置方法,以及线栓端部的处理等。线栓制备等因素的改进大大提高了脑缺血动物模型的成功率。The factors affecting cerebral ischemia model of rat established by middle cerebral artery occlusion include animal selection, drugs of anesthesia, surgical site, thread affect building, and etc. To find and manufacture an appropriate thread is the key to success. It includes the species, length, diameter, hardness, and placing method of the thread. The improvement of these factors greatly increases the successful rate in the establishment of focal cerebra ischemia model of rat caused by middle cerebral artery occlusion.

关 键 词：脑缺血 大鼠 动物模型 综述 

分 类 号：R743.3[医药卫生—神经病学与精神病学]