Biological reduction and intracellular trapping differences of ^(188)Re(VII) and ^(99)Tc^m(VII)in Escherichia coli  

作　　者：XU Fenghua YIN Duanzhi ZHENG Mingqiang WANG Yongxian 

机构地区：[1]Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China [2]Graduate School of Chinese Academy of Sciences, Beijing 100049, China

出　　处：《Nuclear Science and Techniques》2009年第1期27-30,共4页核技术（英文）

基　　金：Supported by the Science&Technology Commission of Shanghai Municipality(No.06DZ19506);the National Natural Science Foundation of China(No.20501022);the Project of Knowledge Innovation of Chinese Academy of Sciences(No.KJCXI-SW-08)

摘　　要：99Tcm is the most commonly used diagnostic radioisotope.And 188Re is an excellent therapeutic radioisotope with a gamma photon for imaging.Both locate in the same group and have very similar properties. 99Tcm(VII)can be partially reduced to a black insoluble precipitate by aerobic cultures of Escherichia coli,and trapped intracellularly.However,188Re(VII)cannot be reduced and trapped,because of its lower oxidizing power of perrhenate as compared with pertechnetate or other reasons.^99Tc^m is the most commonly used diagnostic radioisotope. And ^188Re is an excellent therapeutic radioisotope with a gamma photon for imaging. Both locate in the same group and have very similar properties. ^99Tc^m（Ⅶ） can be parfially reduced to a black insoluble precipitate by aerobic cultures of Escherichia coli, and trapped intracellularly. However, ^188Re（Ⅶ） cannot be reduced and trapped, because of its lower oxidizing power of perrhenate as compared with pertechnetate or other reasons.

关 键 词：放射性同位素 光子 治疗 大肠杆菌 埃希氏菌属 

分 类 号：R574.6[医药卫生—消化系统] O57[医药卫生—内科学]