胃间质瘤11例临床诊治分析  

Diagnosis and Treatment of Gastric Stromal Tumors:A Clinical Analysis of 11 Cases

作　　者：毛岳峰[1] 朱晒红[1] 王国慧[1] 

机构地区：[1]中南大学湘雅三医院普外科,湖南长沙410013

出　　处：《现代生物医学进展》2009年第3期528-529,504,共3页Progress in Modern Biomedicine

摘　　要：目的:探讨胃间质瘤(GST)的诊断和治疗措施。方法:回顾性分析我院2000年4月至2006年3月近6年收治的11例胃间质瘤患者的临床表现、辅助检查、手术治疗方式及病理结果。结果:临床以消化道出血、腹部肿块表现为主,症状无特异性,所有病例术前均行胃镜及CT检查,均行手术治疗,其中6例行肿瘤楔形切除,5例行胃大部切除术,病理诊断良性5例(45.5%)交界性1例(9%),恶性5例(45.5%)。随访时间3个月至5年,死亡1例,死于腹腔广泛转移。结论:胃间质瘤缺乏特异的临床表现,术前诊断困难,胃镜和CT可发现病变,诊断以病理诊断为准,其中免疫组化结果为重要诊断依据,治疗以手术切除为主。Objective： To study the gastric stromal tumors （GST） in the diagnosis and treatment measures. Methods： We reviewed and analyzed the clinical manifestations, auxiliary examination, surgical treatment and pathology results of the 11 cases of gastric stromal tumors in our hospital from April 2000 to March 2006. Results： Gastrointestinal bleeding and abdominal mass are the main clinical symptoms, and no specific symptoms was discovered. All cases had gastroscope and CT scan and underwent surgery. Six of them had tumor wedge resection, and the other five had subtotal gastrectomy, five cases were pathology-diagnosed benign tumor （45.5%）, one was the borderline tumor （9%）, the other five cases were vicious （45.5%）. During the follow-up period of 3 months to 5 years, there was one case of death, which died of abdominal extensive transfer. Conclusions： Gastric stromal tumor lack of specific clinical manifestations, hereby the preoperative diagnosis is very difficult, although the lesions could be find by endoscopy and CT. Pathologic diagnosis is used as the gold standard, for immunohistochemical results is the important basis for the diagnosis. Surgical resection is mostly used to treat it.

关 键 词：胃间质瘤 诊断 手术治疗 

分 类 号：R735.2[医药卫生—肿瘤]