使用MSCT灌注法研究受体肝多期扫描的最佳延迟时间  

Optimication of Delay Time in Multiphasic Enhanced CT Scan of Recipient Liver Using CT Perfusion Technique

作　　者：丁莺[1] 严福华[1] 徐鹏举[1] 陈刚[1] 缪熙音[1] 曾良斌[1] 

机构地区：[1]复旦大学附属中山医院放射科(上海市影像医学研究所),上海200032

出　　处：《放射学实践》2009年第2期175-178,共4页Radiologic Practice

摘　　要：目的:探讨64层螺旋CT灌注方法在确定肝移植受体肝脏多期增强扫描最佳延迟时间中的应用价值。方法:选取拟接受肝移植术患者25例(男17例、女8例),采用5ml/s的注射流率经外周静脉注入对比剂50ml,行肝门层面同层动态扫描。运用CT灌注的后处理方式绘制腹主动脉、门静脉强化的时间-密度曲线,获得肝动脉、门静脉的强化峰值及其达峰时间并行统计学分析。结果:腹主动脉平均最大强化值(288±20.14)HU、平均达峰时间(18.48±1.046)s,门脉主干平均最大强化值(135.12±24.91)HU、平均达峰时间(35.36±2.139)s,门脉达峰后平台期持续时间19.5s。结论:64层螺旋CT灌注方法可以用于确定肝移植受体肝脏多期增强扫描的最佳延迟时间。分别为动脉早期18s,动脉晚期35s,门脉期50s,延迟期85s。其中动脉晚期结合肝脏延迟期扫描有利于肝内富血供病灶的检出和定性诊断。Objective： To discuss the value of CT perfusion technique with 64-slice spiral CT in defining of the optimal delay time of multiphasic contrast enhanced scan in liver transplantation recipient. Methods ： Twenty five patients who anticipated undergoing liver transplantation （17 males,8 females） were enrolled in the study. After intravenous injection of 50ml contrasrt medium at a rate of 5ml/s, the single level dynamic scan was performed through the hepatic portal with eight slices. With application of CT perfusion technique,the time density curves of aorta and portal vein were acquired. The data about the enhanced peak attenuation and TTP （time to peak） of aorta and portal vein were obtained and analysed statistical ly. Results： The average enhanced peak attenuation values of aorta and portal vein were respectively （288 ± 20. 14）HU and （135.12±24.91）HU. The average TTP of aorta and portal vein were respectively （18.48±1. 046）s and （35.36±2. 139）s. The platform period of portal vein after peak was 19. 5s. Conclusion： The optimal delay times of multiphasic eontrasven hanced scan with 64 slice spiral CT in liver transplantation recipient are as follows：the early arterial phase starts at 18s,late arterial phase at 35s,portal vein phase at 50s and liver parenchyma phase at 85s. Besides that,the late arterial phase combined with the liver parenchyma phases scan helpful in the detection and characteristic diagnosis of hypervascular lesion.

关 键 词：肝 肝移植 图像增强 体层摄影术 X线计算机 

分 类 号：R816.5[医药卫生—放射医学]