近红外反射光谱法和多变量统计分类技术用于磺胺噻唑质量评价的研究  

Quality evaluation of sulfathiazole by using near infrared reflectance spectroscopy and multivariate statistical classification techniques

作　　者：任玉林[1] 李伟[1] 苟玉慧[1] 任瑞雪 李玫 孙莹 陈博 

机构地区：[1]吉林大学化学系,长春130023 [2]208医院药剂科,长春130026 [3]长春高等医学专科学校药学系,长春130000

出　　处：《分析仪器》1998年第1期43-47,共5页Analytical Instrumentation

摘　　要：研究了近红外反射光谱法用于磺胺噻唑粉末药品质量评价的可能性。采用多变量统计分类技术（系统聚类分析、逐步聚类分析、主成分分析和逐步判别分析），从磺胺噻唑粉末药品的一阶导数光谱中，成功地鉴别了合格药、劣药和假药。The possibility of using near infrared reflectance spectroscopy (NIRS) to evaluate quality of sulfathiazole is investigated. Multivariate statistical classification techniques (hierarchical analysis, stepwiss analysis, principal component analysis and stepwise discriminant analysis) have been used for identifying qualified, poor and false pharmaceuticals of salfathiazole accordng to their first derivative spectra obtained by NIRS. The results are satisfactory.

关 键 词：磺胺噻唑 质量评价 近红外 反射光谱法 多变量 

分 类 号：R978.2[医药卫生—药品]